Study of XB010 in Subjects With Solid Tumors

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a FIH study is to evaluate the safety, tolerability, PK, immunogenicity, and preliminary antitumor activity of XB010 as a single agent and in combination with pembrolizumab in subjects with locally advanced or metastatic solid tumors for whom alternative therapies do not exist or available therapies are intolerable or no longer effective.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Osoby w wieku 18 lat lub starsze.
  • Stan ogólny pozwalający na codzienne czynności (np. samodzielne poruszanie się).
  • Dobre wyniki badań krwi i prawidłowe działanie narządów.
  • Potwierdzony nowotwór lity, który nie nadaje się do operacji lub rozprzestrzenił się.
  • Możliwość przestrzegania zasad badania i podpisanie zgody na udział.
  • Pacjenci z rakiem płuca (niezwykłkokomórkowym), rakiem piersi (hormonowrażliwym lub potrójnie ujemnym), rakiem głowy i szyi lub rakiem przełyku.

✗ Disqualifies

  • Osoby, które nie spełniają powyższych kryteriów kwalifikacji.
  • Osoby, które uczestniczą w innym badaniu klinicznym.
  • Kobiety w ciąży lub karmiące piersią.

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
June 22, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (20)

City of Hope Orange County Lennar Foundation Cancer Center

Irvine, United States

UCLA Department of Medicine - Hematology/Oncology

Los Angeles, United States

Georgetown University Medical Center

Washington D.C., United States

Sarah Cannon Research Institute at Florida Cancer Specialists

Orlando, United States

Winship Cancer Institute

Atlanta, United States

University of Chicago Medical Center

Chicago, United States

Siteman Cancer Center

St Louis, United States

Montefiore Medical Center - Montefiore Medical Park

The Bronx, United States

Carolina BioOncology Institute

Huntersville, United States

Stephenson Cancer Center

Oklahoma City, United States

SCRI Oncology Partners

Nashville, United States

NEXT Austin

Austin, United States

Baylor University Medical Center

Dallas, United States

University of Texas MD Anderson Cancer Center

Houston, United States

Inova Schar Cancer

Fairfax, United States

NEXT Virginia

Fairfax, United States

University Hospitals of Leicester NHS Trust

Leicester, United Kingdom

Sarah Cannon Research Institute London

London, United Kingdom

University College London Hospitals NHS Foundation Trust

London, United Kingdom

The Christie NHS Foundation Trust

Manchester, United Kingdom

Trial contact

Backup or International

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

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