Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a first-in-human, multicenter, open-label, phase 1 study to evaluate safety, tolerability, and efficacy of CID-078, a Cyclin A/B-RxL inhibitor, in patients with advanced solid tumors.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Potwierdzony guz lity, miejscowo zaawansowany lub z przerzutami, oporny na dostępne leczenie
  • Lub rak piersi potrójnie ujemny/drobnokomórkowy rak płuca/guz lity z określonymi zmianami genetycznymi (RB1, CDKN2A/B)
  • Mierzalna choroba
  • Wiek od 18 lat
  • Dobry stan sprawności (ECOG 0-1)
  • Oczekiwane przeżycie >12 tygodni
  • Możliwość pobrania świeżej biopsji
  • Zdolność połykania kapsułek
  • Prawidłowa funkcja nerek, wątroby i krwi

Simplified criteria — AI translation

Trial details

Minimum age
12 Years
Last updated (source)
September 15, 2025
Sex
No restrictions

Therapies / drugs in trial

Locations (10)

Florida Cancer Specialists

Sarasota, United States

Dana Farber Cancer Institute

Boston, United States

START Midwest

Grand Rapids, United States

Comprehensive Cancer Centers of Nevada

Las Vegas, United States

UH Seidman Cancer Center

Cleveland, United States

Oregon Health and Science University

Portland, United States

Sarah Cannon Research Institute

Nashville, United States

MD Anderson Cancer Center

Houston, United States

NEXT Oncology

San Antonio, United States

START Mountain

West Valley City, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

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