A Study of Sotorasib in People With Non-Small Cell Lung Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The researchers are doing this study to see if sotorasib is a safe and effective treatment for people with advanced non-small cell lung cancer (NSCLC) with a KRAS G12C mutation who have not received treatment for their cancer since it became advanced. (Participants have not received a "first-line therapy" since their cancer became advanced.)
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzony przez badanie wznowiony lub przerzutowy rak płuca
- •Posiadanie mutacji KRAS G12C potwierdzonej w badaniu biopsji lub teście krwi
- •Brak wcześniejszego leczenia zaawansowanego raka
- •Mierzalne ogniska nowotworu
- •Dobry ogólny stan zdrowia (co najmniej 70% zdolności do codziennych czynności)
- •Prawidłowe wyniki badań krwi i funkcji wątroby oraz nerek
- •Zgoda na biopsję przed rozpoczęciem leczenia i w pierwszych tygodniach badania
✗ Disqualifies
- •Wcześniejsze leczenie chemioterapią lub immunoterapią na etapie zaawansowanego raka
- •Kobioty w wieku rozrodczym nieposługujące się skuteczną antykoncepcją
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 11, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (7)
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester
Harrison, United States
Memorial Sloan Kettering Cancer Center
New York, United States
Memorial Sloan Kettering Nassau
Uniondale, United States
Trial contact
Gregory Riely, MD, PhD
Kathryn Arbour, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/12/2026.
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