RecruitingPhase IIEN originalMelanomaMetastatic / advanced

LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study is being done to answer the following question: Can the chance of melanoma growing or spreading be lowered by receiving a treatment called LND101 for Fecal Microbiota Transplant (FMT) in addition to the usual immunotherapy treatment called Immune Checkpoint Blockade (ICB)? FMT treatment changes the bacteria in your gut called the microbiome.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Potwierdzony czerniak skóry lub czerniak nieznanego pochodzenia
  • •Choroba zaawansowana (stadium IV) lub nieoperacyjna
  • •Brak wcześniejszego leczenia immunologicznego (ICB) na czerniakiem zaawansowanym
  • •Wiek co najmniej 18 lat
  • •Możliwość łykania kapsułek
  • •Dostęp do bezpłatnego leczenia immunologicznego finansowanego przez provincję
  • •Zgoda na pobranie próbek krwi i stolca do badań
  • •Zdolność do pracy i samoopieki (ocena funkcjonalna 0-2)

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
September 15, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (15)

BCCA - Abbotsford

Abbotsford British Columbia, Canada

BCCA - Surrey

Surrey, Canada

BCCA - Vancouver

Vancouver, Canada

Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Canada

London Health Sciences Centre Research Inc.

London, Canada

Stronach Regional Health Centre at Southlake

Newmarket, Canada

Ottawa Hospital Research Institute

Ottawa, Canada

Odette Cancer Centre

Toronto, Canada

University Health Network

Toronto, Canada

Centre Integre de Sante et de Services Sociaux

Greenfield Park, Canada

CHUM-Centre Hospitalier de l'Universite de Montreal

Montreal, Canada

The Jewish General Hospital

Montreal, Canada

The Research Institute of the McGill University

Montreal, Canada

Hotel-Dieu de Quebec

Québec, Canada

Centre hospitalier regional de Trois-Rivieres

Trois-Rivières, Canada

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/16/2026.

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