Study in Patients With Breast Cancer Leptomeningeal Metastasis
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Traditional clinical trials in patients with breast cancer leptomeningeal disease (LMD) are challenging as patients often have a rapidly progressive course and prognosis is poor, making meeting standard eligibility difficult. Furthermore, there is limited information about the biology of LMD. The investigators thus propose a study that is as inclusive as possible, which will allow the investigators to collect biospecimens and clinical outcomes to learn more about LMD biology, but still potentially provide benefit for patients, by providing patients rapid diagnostics and multi-disciplinary treatment recommendations.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Kobieta lub mężczyzna w wieku 18 lat lub starszy
- •Historia raka piersi (dowolny typ)
- •Podejrzenie przerzutów raka piersi do opon mózgowych potwierdzone objawami, wynikami badań obrazowych lub analizy płynu mózgowo-rdzeniowego
- •Wcześniejsze przerzuty do ośrodkowego układu nerwowego są dopuszczalne
- •Wystarczająca sprawność fizyczna pacjenta (ocena ECOG ≤3 lub skala Karnofskiego ≥60)
✗ Disqualifies
- •Podejrzenie przerzutów do mózgu pochodzących z białaczki, chłoniaka lub innego nowotworu
- •Pacjent nie kwalifikuje się do leczenia przerzutów do opon mózgowych
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Weeks
- Last updated (source)
- November 28, 2025
- Sex
- No restrictions
Locations (2)
Sibley Memorial Hospital
Washington D.C., United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, United States
Trial contact
Hopkins Breast Trials
Sidney Kimmel Cancer Center Clinical Research Office
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.
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