RecruitingPhase I/IIEN originalColorectal cancerMetastatic / advanced

Safety of HRX215 in Patients After Minor and Major Liver Resection

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The goal of this clinical trial is to learn if HRX215 is safe, tolerable and active in adults who have undergone liver resection due to colorectal carcinoma metastases. The objectives are: 1. to learn about the safety and tolerability of HRX215 2. to learn about how the body absorbs, distributes, and gets rid of HRX215. 3. to learn about clinical activity of HRX215 Researchers will compare HRX215 to a placebo (a look-alike substance that contains no drug) to investigate safety, tolerability and clinical activity in participants taking HRX215.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Pacjenci z przerzutami raka jelita grubego w wątrobie, którzy mają mieć usuniętą część wątroby.
  • Pacjenci stabilni 1-3 dni po mniejszej operacji wątroby (tylko dla części 1 badania).
  • Pacjenci po większej operacji wątroby (tylko dla części 2 i 3 badania).
  • Niskie ryzyko problemów z wątrobą po operacji.

✗ Disqualifies

  • Marskość wątroby.
  • Obecność płynu w jamie brzusznej przed operacją.
  • Inny nowotwór wątroby lub dróg żółciowych.
  • Wskaźnik BMI powyżej 35.

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
75 Years
Last updated (source)
July 10, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (12)

Johns Hopkins Hospital

Baltimore, United States

Mayo Clinic

Rochester, United States

Cleveland Clinic

Cleveland, United States

Centre Hospitalier Régional Universitaire de Lille (CHRU) Hôpital Claude Huriez

Lille, France

Hôpital Paul-Brousse - Centre Hepato-Biliaire (CHB)

Villejuif, France

Univ. Tuebingen - Universitaetsklinik fuer Allgemeine, Viszeral- und Transplantationschirurgie

Tübingen, Germany

Rabin Medical Center

Petah Tikva, Israel

Sheba Medical Center

Ramat Gan, Israel

Tel-Aviv Sourasky MC

Tel Aviv, Israel

Hospital Universitario La Paz

Madrid, Spain

South Texas Accelerated Research Therapeutics Madrid - CIOCC - Universitario Sanchinarro

Madrid, Spain

Consorci Hospital General Universitari de València

Valencia, Spain

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.

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