The AIDPRO-CRC Trial
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The AIDPRO-CRC trial aims to improve outcomes for patients undergoing surgery for colorectal cancer by using artificial intelligence (AI) to assist surgeons in risk assessment. The trial will evaluate whether AI can help surgeons better predict the risk of complications and death, leading to improved care, fewer complications, and better use of healthcare resources. In this nationwide, randomized clinical trial, participants will be divided into two groups. One group will have their risk assessed by a surgeon using standard clinical methods, while the other group will have their risk assessed by a surgeon using AI assistance. Based on the risk level, patients will receive varying levels of perioperative care. The AI-assisted risk assessment aims to tailor the treatment more precisely to each patient's individual needs, precisely allocating care to those who need it to more efficiently allocate heath system resources while having no deterioration in patient outcomes. The primary hypothesis is that AI-assisted risk assessment will lead to more efficient and economic patient care without a deterioration in patient outcomes. The trial also aims to explore clinician satisfaction with the platform and its perceived effect. This is paired with a substudy exploring the variability of suggested treatment plans by clinicians with and without access to the MDT presentation platform. The trial will include patients at seven hospitals across Denmark, involving patients diagnosed with colorectal cancer who are scheduled for curative surgery. All patients will receive standard treatment according to national guidelines, with the only difference being the modality of risk assessment. For the evaluation of the clinicians satisfactory with the device and the substudy of variability of suggested treatment plans, the trial will enroll clinicians using the device. This study is a researcher-initiated, nationwide, randomized clinical trial involving patients diagnosed with colorectal cancer across eight hospitals in Denmark. Participants will be randomly assigned to one of two groups: AI-assisted risk assessment or standard surgeon-led assessment. The intervention focuses on optimizing perioperative care based on individual risk levels determined by either AI or the surgeon's clinical judgment. The study builds on a successful pilot project (AID-SURG) that showed promising results in reducing complications, hospital stays, and readmissions.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony histologicznie (pobraniem tkanki) lub silnie podejrzewany rak jelita grubego, pierwszy raz w życiu
- •Wiek co najmniej 18 lat
- •Zaplanowana operacja mająca na celu całkowite usunięcie nowotworu
- •Podpisana świadoma zgoda na udział w badaniu
- •Dostępne wszystkie dane medyczne potrzebne dla sztucznej inteligencji
✗ Disqualifies
- •Rezygnacja z operacji usuwanej z powodu raka, mimo wcześniejszej kwalifikacji
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 21, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (8)
Aalborg University Hospital, Department of Gastrointestinal Surgery
Aalborg, Denmark
Bispebjerg Hospital, University of Copenhagen, Digestive disease Center, Department of Surgery
Copenhagen NV, Denmark
Regional Hospital Gødstrup, Department of Surgery
Herning, Denmark
Copenhagen University Hospital - North Zealand, Hillerød, Department of Surgery
Hillerød, Denmark
Copenhagen University Hospital Hvidovre, Gastro Unit, Surgical Division
Hvidovre, Denmark
Regional Hospital Randers, Department of Surgery
Randers, Denmark
Odense University Hospital, Svendborg, Department of Colorectal Surgery
Svendborg, Denmark
Viborg Regional Hospital, Hospitalunit Midt, Department of Surgery
Viborg, Denmark
Trial contact
Ismail Gögenur, Professor
Magnus N Jung, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/22/2026.
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