RecruitingPhase IIEN original

Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The primary objective of this research study is to evaluate the effect of tirzepatide, relative to placebo, as an adjunct to BUP on retention, substance use, and sleep outcomes in individuals with OUD.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Umiarkowane lub ciężkie uzależnienie od opioidów
  • Rozpoczęcie buprenorfiny niedawno (7-60 dni temu) i przyjmowanie odpowiedniej dawki
  • Gotowość do losowego przydzielenia do grupy otrzymującej tirzepatide lub placebo
  • Możliwość zrozumienia badania i wyrazenia świadomej zgody na uczestnictwo
  • Nie być w ciąży ani nie karmić piersią; jeśli możliwa ciąża, test musi być ujemny
  • Jeśli możliwa ciąża, zgoda na stosowanie skutecznych metod antykoncepcji podczas badania i 30 dni po nim
  • Zdolność uczestniczenia w cotygodniowych wizytach przez 6 miesięcy

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 17, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (9)

Gateway Community Services

Jacksonville, United States

IBIS Behavioral Health

Tampa, United States

Ruth M. Rothstein CORE Center

Chicago, United States

The Gibson Center for Behavioral Change

Cape Girardeau, United States

Prisma Health

Greenville, United States

Vanderbilt University Medical Center

Nashville, United States

University of Utah

Salt Lake City, United States

Marshall Health

Huntington, United States

Healthy Minds/Chestnut Ridge

Morgantown, United States

Trial contact

Frankie B Kropp, MS, LICDC

Benjamin T Kropp, MSLS

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/18/2026.

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