RecruitingPhase IIEN originalLung cancer

Adjuvant Chemotherapy +/- Cemiplimab and Sequential Hypofractionated Radiotherapy in Unfit or Elderly Patients With Stage III Lung Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The use of neoadjuvant immuno-chemotherapy could improve survival outcomes of patients eligible for sequential radio-chemotherapy comparing to the benefit already obtained with maintenance immunotherapy.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Zaawansowany rak płuca stadium IIIA, IIIB lub IIIC, który nie może być operacyjnie usunięty
  • Wiek powyżej 70 lat lub poniżej 70 lat z innymi schorzeniami wpływającymi na ogólny stan zdrowia
  • Dobra funkcja płuc (co najmniej 40% normy) i oddychanie
  • Wystarczająca funkcja nerek i wątroby
  • Wystarczająca liczba komórek krwi (białe krwinki, płytki, czerwone krwinki)
  • Ubezpieczenie zdrowotne
  • Obecność markera PD-L1 w guzie

✗ Disqualifies

  • Przeciwwskazania do chemioterapii lub immunoterapii
  • Kwalifikowalność do jednoczesnej radioterapii i chemioterapii

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 11, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (25)

Angers - Centre Paul Papin

Angers, France

Angers - CHU

Angers, France

Avignon - CH

Avignon, France

Boulogne - Ambroise Paré

Boulogne, France

Brest - CHU

Brest, France

Caen - CHU

Caen, France

Caen - CRLCC

Caen, France

Créteil - CHI

Créteil, France

Dijon - CRLCC

Dijon, France

Le Mans - CHG

Le Mans, France

Lille - CRLCC

Lille, France

Marseille - APHM

Marseille, France

Mulhouse - GHRMSA

Mulhouse, France

Paris - Bichat

Paris, France

Paris - Hôpital Cochin

Paris, France

Paris - Tenon

Paris, France

Bordeaux - CHU

Pessac, France

Lyon - HCL

Pierre-Bénite, France

Rennes - CHU

Rennes, France

Rouen - Centre Henri Becquerel

Rouen, France

Nantes - CRLCC

Saint-Herblain, France

Strasbourg - CRLCC

Strasbourg, France

Toulouse - CHU

Toulouse, France

Tours - CHU

Tours, France

Vandoeuvre-lès-Nancy - CRLCC

Vandœuvre-lès-Nancy, France

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/12/2026.

You can help another person

We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.