A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to determine the putative recommended phase 2 dose(s) (RP2Ds) and best way to take (optimal route of administration) JNJ-89402638 and to determine the safety of JNJ-89402638 at the RP2D(s) in participants with metastatic colorectal cancer (mCRC) and metastatic gastric cancer (mGAC) and to determine the safety and tolerability of JNJ-89402638 in combination with bevacizumab or biosimilar with or without chemotherapy in participants with mCRC.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Pacjenci z potwierdzonym rakiem jelita grubego, który nie reaguje na wcześniejsze leczenie.
  • Pacjenci z potwierdzonym rakiem żołądka, który nie reaguje na wcześniejsze leczenie.
  • Choroba musi być widoczna w badaniach obrazowych lub możliwa do oceny.
  • Pacjenci muszą być w dobrym ogólnym stanie zdrowia (według skali ECOG 0-1).
  • Wydolność nerek musi być odpowiednia (GFR >= 30 mL/min).

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 6, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (11)

University of Colorado Denver Anschultz Medical Campus

Aurora, United States

Florida Cancer Specialists

Sarasota, United States

Community Health Network

Indianapolis, United States

Start Midwest

Grand Rapids, United States

Swedish Cancer Institute

Seattle, United States

Severance Hospital Yonsei University Health System

Seoul, South Korea

Asan Medical Center

Seoul, South Korea

Hosp Univ Vall D Hebron

Barcelona, Spain

Hosp Univ Fund Jimenez Diaz

Madrid, Spain

Hosp. Univ. 12 de Octubre

Madrid, Spain

Hosp Univ Hm Sanchinarro

Madrid, Spain

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/7/2026.

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