Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This project adopts a prospective study design. It is scheduled to enroll 60 participants diagnosed with Head and Neck cancer in this hospital, of which 30 are in the experimental group and 30 are in the control group. The purpose of this research is to analyze the skeletal muscle mass changes on images in Head and Neck cancer patients after exercise training and the association with systemic inflammatory markers. Investigators would like to know whether these images and biomarkers predict the prognosis of Head and Neck cancer. Subjects enrolled in the trial will receive 36 times of exercise training after concurrent chemoradiotherapy. Before and after the completion of exercise training, investigators will arrange (1) dual energy X-ray absorptiometry (DXA) to measure the whole-body skeletal muscle mass and appendicular skeletal muscle mass and (2) blood tests for markers of systemic inflammation. In addition to DXA, computed tomography (CT) is another image modality for skeletal muscle mass evaluation. Positron emission tomography - CT or whole-body CT for cancer staging are considered as baseline studies. The routine follow-up CT images are used to analyze the changes after exercise training. If magnetic resonance imaging is also performed during the follow-up period, images will also be collected and assessed as an alternative.If the experimental group can maintain or even improve skeletal muscle mass and can be reflected in blood tests and prognosis, the result may be able to apply on cancer treatment and disease followup.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 20 lat
- •Rak płaskonabłonkowy głowy i szyi
- •Wymaga chemioterapii i radioterapii jednocześnie
- •Ogólny stan zdrowia pozwalający na ćwiczenia
- •Zgoda na badania krwi, ćwiczenia i wszystkie procedury badania
✗ Disqualifies
- •Ogólny stan zdrowia uniemożliwiający ćwiczenia
- •Brak tolerancji na ćwiczenia lub brak możliwości chemioterapii i radioterapii
- •Choroby psychiczne lub inne schorzenia, które mogą się pogorszyć przez ćwiczenia
- •Stan zdrowia niesprzyjający ćwiczeniom fizycznym
- •Brak zgody na ćwiczenia, badania krwi i inne procedury badania
- •Brak możliwości wykonania badania tomograficznego całego ciała
Simplified criteria — AI translation
Trial details
- Minimum age
- 20 Years
- Maximum age
- 80 Years
- Last updated (source)
- August 10, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
New Taipei City TuCheng Hospital
New Taipei City, Taiwan
Trial contact
Shao-Chung Wang, PhD
Chia-Hsun Hsieh, PhD
Contact information from ClinicalTrials.gov. Contact in English.
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Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/11/2026.
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