RecruitingPhase IIIEN originalLung cancerMetastatic / advanced

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination of drugs? This study is being done to find out if this approach is better or worse than the usual approach for lung cancer. The usual approach is defined as the care most people get for non-small cell lung cancer.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Zaawansowany rak płuca (etap IV) potwierdzony badaniem obrazowym i histologicznie
  • Nowotwór nie posiada mutacji pozwalającej na celowaną terapię pierwszego rzędu
  • Pogorszenie choroby po co najmniej 3 cyklach standardowego leczenia immunoterapią lub immunoterapią z chemioterapią
  • Wszystkie widoczne ogniska choroby mogą być bezpiecznie leczone zaawansowaną radioterapią
  • Pacjenci z przerzutami do mózgu, które są stabilne i nie powodują objawów
  • Wiek minimum 18 lat
  • Ogólny stan zdrowia oceniony na 0-2 w skali wydolności
  • Ukończył poprzednie leczenie co najmniej 6 miesięcy temu przed rozpoczęciem nowego leczenia

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 14, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (75)

Mayo Clinic Hospital in Arizona

Phoenix, United States

City of Hope Comprehensive Cancer Center

Duarte, United States

City of Hope at Irvine Lennar

Irvine, United States

Saint Mary's Hospital and Regional Medical Center

Grand Junction, United States

CTCA at Southeastern Regional Medical Center

Newnan, United States

Saint Luke's Cancer Institute - Boise

Boise, United States

Saint Luke's Cancer Institute - Fruitland

Fruitland, United States

Saint Luke's Cancer Institute - Meridian

Meridian, United States

Saint Luke's Cancer Institute - Nampa

Nampa, United States

Alton Memorial Hospital

Alton, United States

Northwestern University

Chicago, United States

Decatur Memorial Hospital

Decatur, United States

Northwestern Medicine Cancer Center Kishwaukee

DeKalb, United States

Crossroads Cancer Center

Effingham, United States

Northwestern Medicine Cancer Center Delnor

Geneva, United States

Northwestern Medicine Glenview Outpatient Center

Glenview, United States

Northwestern Medicine Grayslake Outpatient Center

Grayslake, United States

Northwestern Medicine Lake Forest Hospital

Lake Forest, United States

HSHS Saint Elizabeth's Hospital

O'Fallon, United States

Northwestern Medicine Oak Brook

Oak Brook, United States

Northwestern Medicine Orland Park

Orland Park, United States

Memorial Hospital East

Shiloh, United States

Northwestern Medicine Cancer Center Warrenville

Warrenville, United States

UI Health Care Mission Cancer and Blood - Ankeny Clinic

Ankeny, United States

Mercy Hospital

Cedar Rapids, United States

Oncology Associates at Mercy Medical Center

Cedar Rapids, United States

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, United States

Iowa Methodist Medical Center

Des Moines, United States

UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, United States

Mercy Medical Center - Des Moines

Des Moines, United States

UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, United States

UI Healthcare Mission Cancer and Blood - Pella

Pella, United States

UI Health Care Mission Cancer and Blood - Waukee Clinic

Waukee, United States

Miller-Dwan Hospital

Duluth, United States

Mayo Clinic in Rochester

Rochester, United States

Coborn Cancer Center at Saint Cloud Hospital

Saint Cloud, United States

Saint Francis Medical Center

Cape Girardeau, United States

Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, United States

Siteman Cancer Center at West County Hospital

Creve Coeur, United States

Washington University School of Medicine

St Louis, United States

Siteman Cancer Center-South County

St Louis, United States

Siteman Cancer Center at Christian Hospital

St Louis, United States

Nebraska Medicine-Bellevue

Bellevue, United States

Nebraska Medicine-Village Pointe

Omaha, United States

University of Nebraska Medical Center

Omaha, United States

Northwell Health/Center for Advanced Medicine

Lake Success, United States

Mount Sinai Chelsea

New York, United States

Mount Sinai West

New York, United States

Mount Sinai Hospital

New York, United States

Manhattan Eye Ear and Throat Hospital

New York, United States

Lenox Hill Hospital

New York, United States

Queens Cancer Center

Rego Park, United States

University of Rochester

Rochester, United States

Stony Brook University Medical Center

Stony Brook, United States

State University of New York Upstate Medical University

Syracuse, United States

Montefiore Medical Center-Einstein Campus

The Bronx, United States

Montefiore Medical Center - Moses Campus

The Bronx, United States

Ohio State University Comprehensive Cancer Center

Columbus, United States

University of Oklahoma Health Sciences Center

Oklahoma City, United States

Geisinger Medical Center

Danville, United States

Penn State Milton S Hershey Medical Center

Hershey, United States

Geisinger Medical Oncology-Lewisburg

Lewisburg, United States

UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion

Mechanicsburg, United States

Thomas Jefferson University Hospital

Philadelphia, United States

UPMC-Shadyside Hospital

Pittsburgh, United States

Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, United States

Vanderbilt University/Ingram Cancer Center

Nashville, United States

The Don and Sybil Harrington Cancer Center

Amarillo, United States

VCU Massey Cancer Center at Stony Point

Richmond, United States

VCU Massey Comprehensive Cancer Center

Richmond, United States

Northwest Wisconsin Cancer Center

Ashland, United States

Cross Cancer Institute

Edmonton, Canada

CancerCare Manitoba

Winnipeg, Canada

Odette Cancer Centre- Sunnybrook Health Sciences Centre

Toronto, Canada

University Health Network-Princess Margaret Hospital

Toronto, Canada

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/15/2026.

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