Adjuvant Therapy for Intermediate Risk HER2 Positive, Lymph Node Negative Early Breast Cancer With Chemotherapy Combined Target Therapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Human epidermal growth factor receptor 2 (HER2) positive breast cancer is a molecular subtype with high malignancy and easy recurrence and metastasis. The emergence of HER2 targeted drugs has greatly improved the prognosis and survival of such patients. At present, for HER2 positive breast cancer patients with negative lymph nodes, chemotherapy drugs combined with trastuzumab is the current standard treatment scheme, and in most cases, chemotherapy uses a combination of two drugs, while the main beneficiaries of the trastuzumab and pertuzumab are concentrated in the group of patients with positive lymph nodes. Can targeted therapy be used to reduce the progression of chemotherapy and further achieve efficient and low toxicity strategies. It is planned to explore the efficacy and safety of T1-T2, HER2 positive early breast cancer patients with negative lymph nodes to achieve chemotherapy reduction based on risk stratification.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Leczenie w Szpitalu Ludowym Uniwersytetu Pekińskiego z całkowitym usunięciem guza piersi i dokumentacją hospitalizacji
- •Potwierdzony rak piersi w badaniu po operacji z określonym stopniem zaawansowania i cechami genetycznymi spełniającymi kryteria badania
- •Podpisana zgoda na uczestnictwo w badaniu kohortowym chorób piersi
✗ Disqualifies
- •Brak pełnych danych medycznych (zdjęcia, wyniki badań)
- •Otrzymanie chemioterapii przed operacją
- •Rak piersi z przerzutami lub dwustronny rak piersi
- •Niepoddanie się operacji chirurgicznej lub jej niepowodzenie
Simplified criteria — AI translation
Trial details
- Last updated (source)
- December 2, 2024
- Sex
- No restrictions
Locations (1)
Peking University People's Hospital
Beijing, China
Trial contact
yuan peng, doctor
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.
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