SMARTER: Using Blood Samples to iMprove FIT-bAsed coloRecTal cancEr scReening
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The project aims to investigate whether colorectal cancer screening can be improved using blood tests, thereby reducing the number of unnecessary colonoscopies. The Danish colorectal cancer screening program was implemented in 2014, and currently, all individuals aged 50-74 are invited every two years to participate. Those who test positive for hidden blood in their stool are referred for a colonoscopy. More than a third of the approximately 25,000 colonoscopies performed annually in the screening program can be classified as unnecessary, as they reveal a normal colon. This results in avoidable and unpleasant procedures for individuals and strains healthcare resources. The project seeks to reduce the number of these unnecessary colonoscopies by investigating whether blood biomarkers can identify individuals at very low risk of colorectal cancer after a positive stool test for hidden blood. By utilizing blood tests, screening could become more personalized, precise, and resource-efficient for the healthcare system.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Uczestniczysz w programie badań przesiewowych w kierunku raka jelita grubego.
✗ Disqualifies
- •Nie ukończyłeś/aś kolonoskopii, chyba że była ona niemożliwa z powodu guza w jelicie.
Simplified criteria — AI translation
Trial details
- Minimum age
- 50 Years
- Maximum age
- 74 Years
- Last updated (source)
- June 29, 2026
- Sex
- No restrictions
Locations (2)
Hospital Sønderjylland
Aabenraa, Denmark
Vejle Hospital
Vejle, Denmark
Trial contact
Line Fly, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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