A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Banner MD Anderson Cancer Center ( Site 0165)

Gilbert, United States

Banner MD Anderson Cancer Center - University Medical Center Phoenix ( Site 0167)

Phoenix, United States

The University of Arizona Cancer Center - North Campus ( Site 0124)

Tucson, United States

Providence Medical Foundation-Oncology ( Site 0168)

Fullerton, United States

MemorialCare Health System - Long Beach Medical Center ( Site 9559)

Long Beach, United States

Cancer Blood and Specialty Clinic ( Site 0109)

Los Alamitos, United States

Cedars-Sinai Medical Center ( Site 0115)

Los Angeles, United States

Pacific Hematology Oncology Associates ( Site 0131)

San Francisco, United States

Lutheran Hospital - Cancer Centers of Colorado ( Site 0180)

Golden, United States

Clermont Oncology Center ( Site 0182)

Clermont, United States

Bioresearch Partner ( Site 0157)

Hialeah, United States

Orlando Health Cancer Institute ( Site 0169)

Ocoee, United States

Mid Florida Hematology and Oncology Center ( Site 0172)

Orange City, United States

Cancer Care Specialists of Illinois ( Site 0152)

O'Fallon, United States

Fort Wayne Medical Oncology and Hematology ( Site 0149)

Fort Wayne, United States

Cotton O'Neil Cancer Center ( Site 0108)

Topeka, United States

University of Kentucky ( Site 0106)

Lexington, United States

Norton Women's and Children's Hospital-Norton Cancer Institute - St. Matthews ( Site 0163)

Louisville, United States

Owensboro Medical Health System ( Site 0195)

Owensboro, United States

CHRISTUS St. Frances Cabrini Hospital Center for Cancer Care ( Site 0184)

Alexandria, United States

American Oncology Partners, P.A. ( Site 0185)

Bethesda, United States

Karmanos Cancer Institute ( Site 0174)

Detroit, United States

Corewell Health ( Site 0130)

Grand Rapids, United States

The University of Mississippi Medical Center ( Site 0161)

Jackson, United States

Circuit Clinical - SSM Health Cancer Care DePaul ( Site 0166)

Bridgeton, United States

Truman Medical Center ( Site 0122)

Kansas City, United States

Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana ( Site 0178)

Billings, United States

OptumCare Cancer Care ( Site 0121)

Las Vegas, United States

Comprehensive Cancer Centers of Nevada ( Site 0113)

Las Vegas, United States

New York Oncology Hematology, P.C. ( Site 0129)

Albany, United States

Icahn School of Medicine at Mount Sinai ( Site 0164)

New York, United States

Sanford Health Roger Maris Cancer Center ( Site 0189)

Fargo, United States

Prisma Health - Upstate ( Site 0158)

Greenville, United States

Sanford Cancer Center ( Site 0143)

Sioux Falls, United States

The University of Tennessee Medical Center ( Site 0142)

Knoxville, United States

Center for Oncology and Blood Disorders ( Site 0153)

Houston, United States

Houston Methodist Cancer Center ( Site 0154)

Houston, United States

University of Virginia Cancer Center ( Site 0138)

Charlottesville, United States

Virginia Cancer Institute ( Site 0148)

Richmond, United States

Blue Ridge Cancer Care ( Site 0132)

Roanoke, United States

Vista Oncology ( Site 4201)

Olympia, United States

SSM Health Dean Medical Group ( Site 0140)

Madison, United States

Clinica Adventista Belgrano ( Site 0309)

Caba., Argentina

Instituto de Investigaciones Clinicas Mar del Plata ( Site 0306)

Mar del Plata, Argentina

Hospital Universitario Austral ( Site 0307)

Pilar, Argentina

Hospital Aleman ( Site 0301)

Buenos Aires, Argentina

Fundacion Estudios Clinicos ( Site 0311)

Rosario, Argentina

C.I.C.E. 9 de Julio ( Site 0305)

San Miguel de Tucumán, Argentina

Hospital Italiano de Buenos Aires ( Site 0304)

CABA, Argentina

Clinica EL Castaño ( Site 0312)

San Juan, Argentina

Townsville University Hospital ( Site 3006)

Douglas, Australia

Royal Adelaide Hospital ( Site 3001)

Adelaide, Australia

Grampians Health ( Site 3003)

Ballarat, Australia

Northern Hospital ( Site 3002)

Melbourne, Australia

Royal Perth Hospital-Haematology ( Site 3004)

Perth, Australia

AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 1102)

Mechelen, Belgium

ASBL CHU Helora - Hôpital de Mons - Site Kennedy ( Site 1103)

Mons, Belgium

CEONC ( Site 0412)

Cascavel, Brazil

Hospital Erasto Gaertner ( Site 0401)

Curitiba, Brazil

Liga Norte Riograndense Contra o Cancer ( Site 0407)

Natal, Brazil

CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina ( Site 0403)

Florianópolis, Brazil

Hope ( Site 0413)

Ribeirão Preto, Brazil

Clinica Advanze ( Site 0411)

São Carlos, Brazil

F. F. R. M. São Jose do Rio Preto ( Site 0404)

SJRP, Brazil

Hospital Paulistano ( Site 0406)

São Paulo, Brazil

Hospital das Clinicas FMUSP ( Site 0402)

São Paulo, Brazil

Cross Cancer Institute ( Site 0205)

Edmonton, Canada

Queen Elizabeth II Health Sciences Centre ( Site 0207)

Halifax, Canada

Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0208)

Hamilton, Canada

Lakeridge Health - The R.S. McLaughlin Durham Regional Cancer Centre (MDRCC) ( Site 0206)

Oshawa, Canada

Sunnybrook Research Institute ( Site 0204)

Toronto, Canada

Biocenter ( Site 0510)

Concepción, Chile

IC La Serena Research ( Site 0504)

La Serena, Chile

Oncocentro Valdivia ( Site 0506)

Valdivia, Chile

Centro de Estudios Clínicos SAGA ( Site 0508)

Santiago, Chile

FALP ( Site 0501)

Santiago, Chile

Clinica Inmunocel ( Site 0503)

Santiago, Chile

Clínica RedSalud Vitacura ( Site 0512)

Santiago, Chile

Bradfordhill ( Site 0502)

Santiago, Chile

Centro de Investigaciones ( Site 0511)

Viña del Mar, Chile

Anhui Provincial Cancer Hospital ( Site 3124)

Hefei, China

Peking University Third Hospital ( Site 3102)

Beijing, China

Beijing Cancer Hospital ( Site 3101)

Beijing, China

Chongqing Cancer Hospital ( Site 3113)

Chongqing, China

Fujian Provincial Cancer Hospital. ( Site 3119)

Fuzhou, China

The First Affiliated Hospital of Xiamen University ( Site 3120)

Xiamen, China

Sun Yat-sen University Cancer Center ( Site 3121)

Guangzhou, China

Zhujiang Hospital of Southern Medical University ( Site 3122)

Guangzhou, China

Affiliated Cancer Hospital of Guangxi Medical University ( Site 3123)

Nanning, China

The Affiliated Hospital of Guizhou Medical University ( Site 3112)

Guiyang, China

Hubei Cancer Hospital ( Site 3125)

Wuhan, China

Affiliated Hospital of Nantong University ( Site 3117)

Nantong, China

Jiangxi Cancer Hospital ( Site 3118)

Nanchang, China

The First Hospital Of Jilin University ( Site 3103)

Changchun, China

Shandong Cancer Hospital ( Site 3108)

Jinan, China

LinYi Cancer Hospital ( Site 3104)

Linyi, China

Fudan University Shanghai Cancer Center ( Site 3115)

Shanghai, China

Shanxi Cancer Hospital ( Site 3106)

Taiyuan, China

1st Affil Hosp of Med College of Xi'an Jiaotong University ( Site 3107)

Xi’an, China

Sichuan Cancer Hospital. ( Site 3111)

Chengdu, China

West China Hospital, Sichuan University ( Site 3110)

Chengdu, China

Institute of Hematology and Blood Diseases Hosp CAMS&PUMC ( Site 3105)

Tianjin, China

Yunnan Province Cancer Hospital ( Site 3109)

Kunming, China

The First Affiliated Hospital, Zhejiang Medical University ( Site 3116)

Hangzhou, China

Hospital Pablo Tobon Uribe ( Site 0604)

Medellín, Colombia

Hospital Universitario San Ignacio ( Site 0607)

Bogotá, Colombia

IMAT S.A.S ( Site 0603)

Montería, Colombia

Oncologos del Occidente ( Site 0601)

Pereira, Colombia

Fundación Valle del Lili ( Site 0602)

Cali, Colombia

University College Hospital, Department of Haematology ( Site 1303)

Aarhus, Denmark

Regionshospitalet Gødstrup ( Site 1301)

Herning, Denmark

Aalborg University Hospital ( Site 1302)

Aalborg, Denmark

Odense Universitetshospital ( Site 1304)

Odense, Denmark

Centre Antoine-Lacassagne ( Site 1514)

Nice, France

Hopital Saint Louis, Centre Hospitalier de La Rochelle ( Site 1511)

La Rochelle, France

CHU Dijon Bourgogne ( Site 1516)

Dijon, France

CHU GRENOBLE ALPES ( Site 1518)

La Tronche, France

Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 1512)

Limoges, France

Centre Hospitalier Régional Metz Thionville - Hôpital de Mercy ( Site 1515)

Metz, France

Centre Hospitalier de Dunkerque ( Site 1513)

Dunkirk, France

Centre Hospitalier Universitaire Estaing ( Site 1508)

Clermont-Ferrand, France

Centre Hospitalier de la Cote Basque ( Site 1509)

Bayonne, France

Centre Henri Becquerel ( Site 1517)

Rouen, France

HIA Sainte Anne ( Site 1506)

Toulon, France

Centre Hospitalier d'Avignon ( Site 1505)

Avignon, France

CHD Vendee ( Site 1502)

La Roche-sur-Yon, France

Institut Curie - site Saint-Cloud ( Site 1501)

Saint-Cloud, France

Evangelismos General Hospital of Athens ( Site 1602)

Athens, Greece

General Hospital of Athens "Laiko"-Hematology Department ( Site 1603)

Athens, Greece

Attikon University General Hospital of Athens ( Site 1604)

Athens, Greece

University General Hospital of Alexandroupoli ( Site 1601)

Alexandroupoli, Greece

MEDI-K ( Site 0701)

Guatemala City, Guatemala

CELAN,S.A ( Site 0702)

Guatemala City, Guatemala

Cen Integral Onco Gastro y Hemato Onco Guatemala S.A. ( Site 0703)

Guatemala City, Guatemala

Princess Margaret Hospital ( Site 3202)

Hong Kong, Hong Kong

Queen Mary Hospital ( Site 3201)

Hong Kong, Hong Kong

Semmelweis University-Belgyógyászati és Hematológiai Klinika ( Site 1703)

Budapest, Hungary

Debreceni Egyetem Klinikai Kozpont ( Site 1702)

Debrecen, Hungary

Szabolcs Szatmár Bereg Vármegyei Oktatókórház ( Site 1704)

Nyíregyháza, Hungary

Tolna Vármegyei Balassa János Kórház ( Site 1710)

Szekszárd, Hungary

Orszagos Onkologiai Intezet ( Site 1705)

Budapest, Hungary

Carmel Hospital ( Site 1903)

Haifa, Israel

Hadassah Medical Center ( Site 1901)

Jerusalem, Israel

Sourasky Medical Center ( Site 1904)

Tel Aviv, Israel

Poria Medical Center ( Site 1902)

Tiberias, Israel

Fondazione IRCCS San Gerardo dei Tintori ( Site 2008)

Monza, Italy

IRCCS Crob ( Site 2002)

Rionero in Vulture, Italy

Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia ( Site 2010)

Candiolo, Italy

AOU delle Marche Ospedali Riuniti di Ancona ( Site 2011)

Ancona, Italy

Azienda Ospedaliera Spedali Civili di Brescia-Hemathology ( Site 2001)

Brescia, Italy

IRCCS Ospedale San Raffaele ( Site 2012)

Milan, Italy

IEO Istituto Europeo di Oncologia ( Site 2009)

Milan, Italy

Azienda Ospedaliero Universitaria Maggiore della Carità ( Site 2004)

Novara, Italy

Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO ( Site 2005)

Palermo, Italy

Ospedale Santa Maria delle Croci ( Site 2006)

Ravenna, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 2003)

Roma, Italy

Nagoya University Hospital ( Site 3309)

Nagoya, Japan

National Cancer Center Hospital East ( Site 3303)

Kashiwa, Japan

National Hospital Organization Shikoku Cancer Center ( Site 3321)

Matsuyama, Japan

Kobe City Medical Center General Hospital ( Site 3318)

Kobe, Japan

Kanazawa University Hospital ( Site 3308)

Kanazawa, Japan

Tokai University Hospital ( Site 3302)

Isehara, Japan

Tohoku University Hospital ( Site 3301)

Sendai, Japan

Kindai University Hospital ( Site 3310)

Sakai, Japan

Saitama Medical University Hospital ( Site 3305)

Iruma-gun, Japan

Juntendo University Hospital ( Site 3307)

Bunkyo, Japan

Tokyo Metropolitan Komagome Hospital ( Site 3323)

Bunkyo, Japan

University of Yamanashi Hospital ( Site 3320)

Chūō, Japan

Chiba Cancer Center ( Site 3314)

Chiba, Japan

Kyushu University Hospital ( Site 3313)

Fukuoka, Japan

Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital ( Site 3322)

Hiroshima, Japan

University Hospital,Kyoto Prefectural University of Medicine ( Site 3315)

Kyoto, Japan

University of Miyazaki Hospital ( Site 3319)

Miyazaki, Japan

Okayama University Hospital ( Site 3311)

Okayama, Japan

Osaka Metropolitan University Hospital ( Site 3317)

Osaka, Japan

Yamagata University Hospital ( Site 3312)

Yamagata, Japan

Queen Elizabeth Hospital ( Site 3405)

Kota Kinabalu, Malaysia

Sarawak General Hospital ( Site 3402)

Kuching, Malaysia

Hospital Miri ( Site 3403)

Miri, Malaysia

Sunway Medical Centre ( Site 3406)

Petaling Jaya, Malaysia

Hospital Ampang ( Site 3404)

Selangor Darul Ehsan, Malaysia

CIMAB SA de CV ( Site 0807)

Torreón, Mexico

Grupo Ollin Care ( Site 0806)

Pachuca, Mexico

Health Pharma Professional Research S.A. de C.V. ( Site 0801)

Mexico City, Mexico

Centro de Infusion Superare ( Site 0804)

Mexico City, Mexico

Centro de Investigacion Clinica Chapultepec ( Site 0803)

Morelia, Mexico

Hospital Universitario ""Dr. Jose Eleuterio Gonzalez"" ( Site 0802)

Monterrey, Mexico

Centro de Investigacion Clinica de Oaxaca ( Site 0805)

Oaxaca City, Mexico

Albert Schweitzer Ziekenhuis ( Site 2103)

Dordrecht, Netherlands

Meander Medisch Centrum ( Site 2101)

Amersfoort, Netherlands

Clínicas AUNA Sede Chiclayo ( Site 0904)

Chiclayo, Peru

INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 0901)

Surquillo, Peru

Clínica San Felipe ( Site 0906)

Lima, Peru

Hospital Nacional Edgardo Rebagliati Martins ( Site 0903)

Lima, Peru

Hospital Nacional Dos De Mayo ( Site 0905)

Lima, Peru

Pratia Onkologia Wroclaw ( Site 2211)

Wroclaw, Poland

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 2201)

Warsaw, Poland

Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku ( Site 2210)

Słupsk, Poland

Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 2208)

Gliwice, Poland

Pratia Onkologia Katowice ( Site 2204)

Katowice, Poland

Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko-Mazurskim Centrum Onko ( Site 2205)

Olsztyn, Poland

Unidade Local de Saude de Braga - Hospital de Braga ( Site 2306)

Braga, Portugal

Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 2308)

Lisbon, Portugal

Instituto Portugues de Oncologia Do Porto Francisco Gentil E.P.E. ( Site 2302)

Porto, Portugal

Auxilio Mutuo Cancer Center ( Site 1001)

San Juan, Puerto Rico

BRCR Global Puerto Rico - Caribbean Cancer Care ( Site 1003)

Yauco, Puerto Rico

Spitalul Clinic Colțea ( Site 2401)

Bucharest, Romania

Institutul Oncologic Cluj ( Site 2404)

Cluj-Napoca, Romania

Centrul de Diagnostic si Tratament Oncologic Brasov ( Site 2402)

Brasov, Romania

Spital Judetean Sibiu ( Site 2405)

Sibiu, Romania

National University Hospital ( Site 3702)

Singapore, Singapore

National Cancer Centre Singapore ( Site 3701)

Singapore, Singapore

LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 2506)

Pretoria, South Africa

Netcare Pretoria East Hospital ( Site 2502)

Pretoria, South Africa

Haemalife ( Site 2501)

Cape Town, South Africa

Groote Schuur Hospital ( Site 2504)

Cape Town, South Africa

National Cancer Center- Center for Hemotologic malignancy ( Site 3806)

Goyang-si, South Korea

Pusan National University Hospital ( Site 3804)

Busan, South Korea

Chungnam National University Hospital ( Site 3801)

Daejeon, South Korea

Severance Hospital, Yonsei University Health System ( Site 3802)

Seoul, South Korea

Asan Medical Center ( Site 3803)

Seoul, South Korea

Samsung Medical Center ( Site 3807)

Seoul, South Korea

St.Mary's H., Youido ( Site 3805)

Seoul, South Korea

Hospital Universitario Virgen Macarena ( Site 2608)

Seville, Spain

ICO L Hospitalet ( Site 2601)

L'Hospitalet de Llobregat, Spain

H. Insular de Gran Canaria ( Site 2606)

Las Palmas de Gran Canaria, Spain

Hospital Universitario Puerta de Hierro ( Site 2615)

Majadahonda, Spain

Hospital de Cabuenes ( Site 2613)

Gijón, Spain

Hospital General Universitario Dr. Balmis ( Site 2604)

Alicante, Spain

Hospital del Mar ( Site 2610)

Barcelona, Spain

HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON ( Site 2614)

Madrid, Spain

Hospital General Universitario 12 de Octubre ( Site 2605)

Madrid, Spain

Hospital Universitario La Paz ( Site 2611)

Madrid, Spain

Hospital Virgen de la Victoria ( Site 2609)

Málaga, Spain

Hospital Universitario Miguel Servet ( Site 2607)

Zaragoza, Spain

Kantonspital Baden ( Site 2703)

Baden, Switzerland

Cantonal Hospital St.Gallen-Oncology & Hematology ( Site 2702)

Sankt Gallen, Switzerland

Ospedale Regionale Bellinzona e Valli ( Site 2701)

Bellinzona, Switzerland

Ospedale Italiano Lugano (OIL) ( Site 2705)

Lugano, Switzerland

Chang Gung Memorial Hospital - Linkou Branch ( Site 3903)

Taoyuan City, Taiwan

Chang Gung Memorial Hospital at Kaohsiung ( Site 3905)

Kaohsiung City, Taiwan

National Cheng Kung University Hospital ( Site 3902)

Tainan, Taiwan

National Taiwan University Hospital ( Site 3901)

Taipei, Taiwan

Mackay Memorial Hospital ( Site 3908)

Taipei, Taiwan

Tri-Service General Hospital ( Site 3906)

Taipei, Taiwan

Faculty of Medicine Siriraj Hospital ( Site 4001)

Bangkoknoi, Thailand

Chulalongkorn University ( Site 4003)

Pathumwan, Thailand

Maharaj Nakorn Chiang Mai Hospital ( Site 4002)

Muang, Thailand

Ondokuz Mayıs Universitesi ( Site 2806)

Korfez Mahallesi, Turkey (Türkiye)

Namık Kemal University Medical Faculty ( Site 2807)

Suleymanpasa, Turkey (Türkiye)

Baskent Universitesi Adana Dr. Turgut Noyan UAM ( Site 2809)

Adana, Turkey (Türkiye)

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 2803)

Ankara, Turkey (Türkiye)

Hacettepe Universite Hastaneleri ( Site 2810)

Ankara, Turkey (Türkiye)

Ankara University Faculty of Medicine ( Site 2801)

Ankara, Turkey (Türkiye)

Antalya Egitim ve Arastirma Hastanesi ( Site 2805)

Antalya, Turkey (Türkiye)

Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi ( Site 2804)

Istanbul, Turkey (Türkiye)

MNPE ClinCenter of Oncology,Hematology,Transplantology and Palliative Care of CherkasyRegCouncil ( Site 2904)

Cherkasy, Ukraine

Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council" ( Site 2906)

Ivano-Frankivsk, Ukraine

Khmelnytskyi Regional Hospital ( Site 2907)

Khmelnytskiy, Ukraine

Institute of Blood Pathology and Transfusion Medicine AMS Ukraine ( Site 2903)

Lviv, Ukraine

SNPE National Cancer Institute ( Site 2902)

Kyiv, Ukraine

Universal Clinic Oberig ( Site 2908)

Kyiv, Ukraine

SI National Research Center of Radiation Medicine, Hematology, Oncology ( Site 2901)

Kyiv, Ukraine