Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase III trial compares the effect of high dose chemotherapy and the patients' own (autologous) stem cells to observation only in patients with peripheral T-cell lymphoma who achieved a complete response after initial chemotherapy. Usual treatment after a complete response may include observation or high dose chemotherapy followed by an autologous stem cell transplant, however, it is not known if a transplant if beneficial. Giving chemotherapy before a stem cell transplant helps kill cancer cells in the body and helps make room in the patient's bone marrow for new blood-forming cells (stem cells) to grow. Stem cells removed prior to treatment are then returned to the patient to replace the blood forming cells that were destroyed by the chemotherapy. Giving high dose chemotherapy followed by an autologous stem cell transplant may be more effective compared to observation only in treating patients with peripheral T-cell lymphoma who have achieved a complete response after initial chemotherapy.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18-75 lat
- •Potwierdzony chłoniak z komórek T (jeden z czterech określonych typów)
- •Ukończona początkowa chemioterapia zawierająca antracykliny
- •Całkowite ustąpienie nowotworu potwierdzone badaniami obrazowymi po chemioterapii
- •Zdolność do przyjęcia intensywnej chemioterapii i przeszczepu komórek macierzystych
- •Brak aktualnego zakażenia wymagającego leczenia antybiotykami podawanego dożylnie
✗ Disqualifies
- •Ciąża lub karmienie piersią
- •Inne nowotwory, które mogą wpłynąć na bezpieczeństwo badania
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 75 Years
- Last updated (source)
- July 17, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (158)
University of Alabama at Birmingham Cancer Center
Birmingham, United States
Anchorage Associates in Radiation Medicine
Anchorage, United States
Alaska Breast Care and Surgery LLC
Anchorage, United States
Alaska Oncology and Hematology LLC
Anchorage, United States
Alaska Women's Cancer Care
Anchorage, United States
Katmai Oncology Group
Anchorage, United States
Providence Alaska Medical Center
Anchorage, United States
Fairbanks Memorial Hospital
Fairbanks, United States
Mayo Clinic Hospital in Arizona
Phoenix, United States
Banner University Medical Center - Tucson
Tucson, United States
University of Arizona Cancer Center-North Campus
Tucson, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, United States
City of Hope Comprehensive Cancer Center
Duarte, United States
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, United States
Contra Costa Regional Medical Center
Martinez, United States
Providence Queen of The Valley
Napa, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, United States
Providence Medical Foundation - Santa Rosa
Santa Rosa, United States
Providence Santa Rosa Memorial Hospital
Santa Rosa, United States
BASS Medical Group - Lennon
Walnut Creek, United States
Rocky Mountain Cancer Centers-Aurora
Aurora, United States
Boulder Community Foothills Hospital
Boulder, United States
Rocky Mountain Cancer Centers-Boulder
Boulder, United States
Rocky Mountain Cancer Centers - Centennial
Centennial, United States
The Women's Imaging Center
Denver, United States
Colorado Blood Cancer Institute
Denver, United States
Presbyterian - Saint Lukes Medical Center - Health One
Denver, United States
Rocky Mountain Cancer Centers-Midtown
Denver, United States
Rocky Mountain Cancer Centers-Rose
Denver, United States
Rocky Mountain Cancer Centers - Swedish
Englewood, United States
The Melanoma and Skin Cancer Institute
Englewood, United States
Rocky Mountain Cancer Centers-Lakewood
Lakewood, United States
Rocky Mountain Cancer Centers-Littleton
Littleton, United States
Rocky Mountain Cancer Centers-Sky Ridge
Lone Tree, United States
Rocky Mountain Cancer Centers-Longmont
Longmont, United States
Rocky Mountain Cancer Centers-Thornton
Thornton, United States
Beebe Medical Center
Lewes, United States
Beebe South Coastal Health Campus
Millville, United States
Helen F Graham Cancer Center
Newark, United States
Medical Oncology Hematology Consultants PA
Newark, United States
Christiana Care Health System-Christiana Hospital
Newark, United States
Beebe Health Campus
Rehoboth Beach, United States
Christiana Care Health System-Wilmington Hospital
Wilmington, United States
Mayo Clinic in Florida
Jacksonville, United States
Moffitt Cancer Center-International Plaza
Tampa, United States
Moffitt Cancer Center - McKinley Campus
Tampa, United States
Moffitt Cancer Center
Tampa, United States
Emory University Hospital/Winship Cancer Institute
Atlanta, United States
Saint Luke's Cancer Institute - Boise
Boise, United States
Saint Luke's Cancer Institute - Fruitland
Fruitland, United States
Saint Luke's Cancer Institute - Meridian
Meridian, United States
Saint Luke's Cancer Institute - Nampa
Nampa, United States
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, United States
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, United States
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, United States
University of Kansas Cancer Center
Kansas City, United States
University of Kansas Cancer Center-Overland Park
Overland Park, United States
University of Kansas Hospital-Westwood Cancer Center
Westwood, United States
The James Graham Brown Cancer Center at University of Louisville
Louisville, United States
UofL Health Medical Center Northeast
Louisville, United States
Mercy Health - Paducah Cancer Center
Paducah, United States
Ochsner Medical Center Jefferson
New Orleans, United States
LSU Health Sciences Center at Shreveport
Shreveport, United States
Christiana Care - Union Hospital
Elkton, United States
Wayne State University/Karmanos Cancer Institute
Detroit, United States
Weisberg Cancer Treatment Center
Farmington Hills, United States
Mayo Clinic in Rochester
Rochester, United States
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, United States
Siteman Cancer Center at West County Hospital
Creve Coeur, United States
University of Kansas Cancer Center - Briarcliff
Kansas City, United States
University of Kansas Cancer Center - North
Kansas City, United States
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, United States
Washington University School of Medicine
St Louis, United States
Siteman Cancer Center-South County
St Louis, United States
Siteman Cancer Center at Christian Hospital
St Louis, United States
Saint Patrick Hospital - Community Hospital
Missoula, United States
University of Rochester
Rochester, United States
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, United States
Carolinas Medical Center/Levine Cancer Institute
Charlotte, United States
Novant Health Presbyterian Medical Center
Charlotte, United States
Wake Forest University at Clemmons
Clemmons, United States
Duke University Medical Center
Durham, United States
Novant Health Cancer Institute - Huntersville
Huntersville, United States
Novant Health Presbyterian Medical Center Huntersville
Huntersville, United States
Novant Health Cancer Institute - Kernersville
Kernersville, United States
Matthews Radiation Oncology Center
Matthews, United States
Novant Health Cancer Institute - Matthews
Matthews, United States
Novant Health Cancer Institute - Mooresville
Mooresville, United States
Novant Health Cancer Institute - Mount Airy
Mount Airy, United States
Novant Health Cancer Institute - Wilkesboro
North Wilkesboro, United States
Rowan Regional Medical Center
Salisbury, United States
Novant Health Cancer Institute - Statesville
Stateville, United States
Novant Health Cancer Institute - Thomasville
Thomasville, United States
Novant Health Forsyth Medical Center
Winston-Salem, United States
Wake Forest University Health Sciences
Winston-Salem, United States
OhioHealth O'Bleness Hospital
Athens, United States
Columbus Oncology and Hematology Associates Inc
Columbus, United States
Riverside Methodist Hospital
Columbus, United States
Grant Medical Center
Columbus, United States
Doctors Hospital
Columbus, United States
Delaware Health Center-Grady Cancer Center
Delaware, United States
Grady Memorial Hospital
Delaware, United States
Columbus Oncology and Hematology Associates
Dublin, United States
Dublin Methodist Hospital
Dublin, United States
OhioHealth Mansfield Hospital
Mansfield, United States
OhioHealth Marion General Hospital
Marion, United States
OhioHealth Pickerington Methodist Hospital
Pickerington, United States
OhioHealth Westerville Medical Campus/Westerville Cancer Center
Westerville, United States
University of Oklahoma Health Sciences Center
Oklahoma City, United States
Saint Charles Health System
Bend, United States
Clackamas Radiation Oncology Center
Clackamas, United States
Bay Area Hospital
Coos Bay, United States
Providence Hood River Memorial Hospital
Hood River, United States
Providence Newberg Medical Center
Newberg, United States
Providence Willamette Falls Medical Center
Oregon City, United States
Providence Portland Medical Center
Portland, United States
Providence Saint Vincent Medical Center
Portland, United States
Oregon Health and Science University
Portland, United States
Saint Charles Health System-Redmond
Redmond, United States
Christiana Care Health System-Concord Health Center
Chadds Ford, United States
Geisinger Medical Center
Danville, United States
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, United States
Medical University of South Carolina
Charleston, United States
Huntsman Cancer Institute/University of Utah
Salt Lake City, United States
University of Virginia Cancer Center
Charlottesville, United States
VCU Massey Comprehensive Cancer Center
Richmond, United States
Providence Regional Cancer System-Aberdeen
Aberdeen, United States
PeaceHealth Saint Joseph Medical Center
Bellingham, United States
Providence Regional Cancer System-Centralia
Centralia, United States
Swedish Cancer Institute-Edmonds
Edmonds, United States
Providence Regional Cancer Partnership
Everett, United States
Swedish Cancer Institute-Issaquah
Issaquah, United States
Kadlec Clinic Hematology and Oncology
Kennewick, United States
Providence Regional Cancer System-Lacey
Lacey, United States
PeaceHealth Saint John Medical Center
Longview, United States
Skagit Regional Health Cancer Care Center
Mount Vernon, United States
Jefferson Healthcare
Port Townsend, United States
Swedish Medical Center-Ballard Campus
Seattle, United States
Swedish Medical Center-Cherry Hill
Seattle, United States
Swedish Medical Center-First Hill
Seattle, United States
PeaceHealth United General Medical Center
Sedro-Woolley, United States
Cancer Care Northwest - Spokane South
Spokane, United States
Cancer Care Northwest-Valley
Spokane, United States
Cancer Care Northwest-North Spokane
Spokane, United States
PeaceHealth Southwest Medical Center
Vancouver, United States
Providence Saint Mary Regional Cancer Center
Walla Walla, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, United States
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, United States
Marshfield Medical Center-Marshfield
Marshfield, United States
Froedtert Menomonee Falls Hospital
Menomonee Falls, United States
Medical College of Wisconsin
Milwaukee, United States
ProHealth D N Greenwald Center
Mukwonago, United States
Froedtert and MCW Moorland Reserve Health Center
New Berlin, United States
Drexel Town Square Health Center
Oak Creek, United States
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, United States
ProHealth Waukesha Memorial Hospital
Waukesha, United States
UW Cancer Center at ProHealth Care
Waukesha, United States
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend, United States
Trial contact
Pamela Cogliano
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/18/2026.
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