RecruitingPhase IIEN originalColorectal cancerMetastatic / advanced

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a 2-arm, noncomparative phase 2 trial designed to evaluate treatment outcomes with or without the addition of ciprofloxacin, metronidazole, and aspirin to first-line chemotherapy for patients with stage IV colorectal cancer (CRC).

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Rozpoznany rak jelita grubego w stadium IV (zaawansowany)
  • Widoczny guz, który można zmierzyć na badaniach obrazowych
  • Planowane leczenie chemioterapią pierwszej linii
  • Ogólny stan zdrowia pozwalający na leczenie (ECOG 0-2)
  • Odpowiednie wyniki badań krwi: liczba neutrofili, płytki krwi, hemoglobina
  • Dobra funkcja wątroby i nerek
  • Nie w ciąży i nie karmiące piersią
  • Zgoda na stosowanie antykoncepcji podczas badania (osoby w wieku rozrodczym)

✗ Disqualifies

  • Całkowite usunięcie jelita grubego
  • Rozpoznanie zespołu Cockayne'a
  • Przyjmowanie leku disulfiram

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 18, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (2)

Virginia Cancer Institute (VCI)

Richmond, United States

Virginia Commonwealth University

Richmond, United States

Trial contact

Massey IIT Research Operations

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/19/2026.

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