Precision Retrospective Integrative Study for Metastatic Lymph Nodes in Breast Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Accurate assessment of axillary lymph nodes in patients with breast cancer is essential for prognosis and treatment planning. Staging and surgical management have evolved from axillary lymph node dissection to sentinel lymph node biopsy to minimize morbidity. However, sentinel lymph node biopsy has non-negligible morbidity, and more than 70% of biopsies are negative, calling into question its routine use. Magnetic resonance imaging (MRI) can be used to detect and stage lymph node metastases in situ, but its sensitivity and specificity are moderate to poor. Few studies have employed artificial intelligence to detect lymph node metastases on MRI images, and none have used an integrative multidata approach (IMA), defined as modeling the combination of clinical and laboratory data with multiparametric MRI. The primary objective of this retrospective observational study is to improve the accuracy of detecting lymph node involvement in breast cancer using IMA. The secondary objective is to allow longitudinal monitoring of the effects of neoadjuvant therapy on lymph node involvement
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjenci zdiagnozowani z rakiem piersi, u których wykonano rezonans magnetyczny (MRI) i biopsję lub operację węzłów chłonnych w pachwinie
- •Pacjenci wszystkich płci i wieku ze stadium I-III raka piersi
- •Pacjenci, którzy otrzymali leczenie przedoperacyjne i mają dostępne dane z badań obrazowych do analizy
✗ Disqualifies
- •Pacjenci, których zdjęcia MRI były niewystarczającej jakości do analizy
- •Pacjenci z wcześniejszym rakiem piersi w przeszłości
- •Pacjenci, którzy mieli wcześniejszą operację pachwiny lub usunięcie węzłów chłonnych przed obecnym diagnozą raka piersi
- •Pacjenci, którzy otrzymali leczenie przedoperacyjne w innej placówce medycznej
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- December 17, 2024
- Sex
- No restrictions
Locations (4)
Landeskrankenhaus Villach
Villach, Austria
KI4LIFE, Fraunhofer Austria Research
Austria, Italy
Klinikum Klagenfurt am Wörthersee Klagenfurt am Wörthersee
Villach, Italy
Centro di Riferimento Oncologico
Aviano, Italy
Trial contact
Fabio Del Ben, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.
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