A Study of BL0175 Injection in Postmenopausal Female Adults With HR-positive, Locally Advanced or Metastatic Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The goal of this clinical trial is to learn if the investigational drug BL0175 works to treat adult postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor (HER2)-negative locally advanced or metastatic breast cancer, ovarian cancer and endometrial cancer. It will also learn about the safety of BL0175. The main questions it aims to answer are: * Does the investigational drug BL0175 is safe for participants after dosed -multiple times? * Which is the highest safety dose of BL0175 after multiple dose? * What medical problems do participants have when using BL0175? * Does the investigational drug BL0175 works for participants after dosed -multiple times?

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Chęć udziału w badaniu i zgoda na podpisanie formularza świadomej zgody.
  • Osoby w wieku 18 lat i więcej.
  • Kobiety po menopauzie z zaawansowanym lub rozsianym rakiem piersi (hormonozależnym, bez HER2), jajnika lub macicy, który postępował mimo leczenia.
  • Pacjentki z co najmniej jedną zmianą nowotworową, którą można dokładnie ocenić.
  • Ogólny stan zdrowia pozwalający na normalną aktywność (punktacja 0 lub 1 w skali ECOG).
  • Przewidywana długość życia co najmniej 12 tygodni.

✗ Disqualifies

  • Pacjentki z objawowymi przerzutami do mózgu lub zapaleniem opon mózgowo-rdzeniowych spowodowanym przez nowotwór.
  • Pacjentki z innymi pierwotnymi nowotworami.

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
January 13, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (2)

The First Hospital of Jilin University

Changchun, China

Jinan Central Hospital

Jinan, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

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