A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The researchers are doing this study to find out if the study treatment is an effective treatment that causes few or mild side effects in people with diffuse large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma (HGBCL), or transformed lymphoma. The treatment being tested in this study is glofitamab, polatuzumab, and obinutuzumab in combination with standard treatment (the combination of rituximab, cyclophosphamide, doxorubicin, and prednisone, or R-miniCHP).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 65-79 lat z oceną kondycji fizycznej jako słaba lub krucha
- •Wiek 80 lat i powyżej, niezależnie od kondycji fizycznej
- •Potwierdzony rozpoznaniem chłoniak B-komórkowy dużokomórkowy, wysokiej złośliwości lub wtórny
- •Brak wcześniejszego leczenia systemowego tego nowotworu
- •Zaawansowana choroba (stadium 2-4 wg klasyfikacji Ann Arbor)
- •Wystarczająca funkcja serca (sprawdzenie echokardiografią)
- •Mierzalna zmiana nowotworu widoczna w tomografii lub rezonansie
- •Dobra funkcja organów wewnętrznych i szpiku kostnego
Simplified criteria — AI translation
Trial details
- Minimum age
- 65 Years
- Maximum age
- 80 Years
- Last updated (source)
- July 22, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (8)
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Hackensack Meridian Health (Data collection only)
Hackensack, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Cancer Center Suffolk - Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Rockville Centre, United States
Trial contact
Pallawi Torka, MD
Paul Hamlin, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/23/2026.
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