A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult Participants with Advanced Solid Tumors
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzony nowotwór w zaawansowanym stadium, który nie reaguje na standardowe leczenie lub pacjent nie może go otrzymywać
- •Wcześniejsze leczenie przeciwnowotworowe bez skutku - nowotwór progresuje
- •Możliwość zmierzenia zmian nowotworowych w badaniach obrazowych
- •W drugim etapie badania: rak jajnika oporny na platynę, rak nerki, rak płuc lub inne określone typy nowotworów
- •Podpisana świadoma zgoda na udział w badaniu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 17, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (17)
Sarah Cannon Research Institute (SCRI) - Lake Nona
Orlando, United States
Emory Winship Cancer Institute
Atlanta, United States
University Medical Center of New Orleans LSU-LCMC Health Cancer Center
New Orleans, United States
Dana-Farber Cancer Institute
Boston, United States
Hackensack University Medical Center
Hackensack, United States
Roswell Park Cancer Institute
Buffalo, United States
Icahn School of Medicine at Mount Sinai
New York, United States
Sarah Cannon Research Institute (SCRI) - Nashville
Nashville, United States
UT Health San Antonio - Mays Cancer Center
San Antonio, United States
The first medical center of PLA general hospital
Beijing, China
Liaoning Cancer Hospital & Institute
Shenyang, China
The Fourth Hospital of Hebei Medical University (Heibei Tumor Hospital)
Shijiazhuang, China
Sun Yat-sen University Cancer Center
Guangzhou, China
HunanCancer Hospital
Changsha, China
Cancer Hospital of Shandong First Medical University
Jinan, China
Affiliated Hospital of Jining Medical University
Jining, China
Fudan University Shanghai Cancer Center
Shanghai, China
Trial contact
Udayan Guha, PhD, MD
Siyuan Qian
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/29/2026.
You can help another person
We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.