RecruitingPhase IIEN originalLeukemia

Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The goal of this clinical research study is to learn if metal detoxification (with calcium disodium edetate \[Ca-EDTA\] and dimercaptosuccinic acid \[DMSA\]) during standard therapy can help improve outcomes in patients with intermediate-risk, high-risk, or secondary AML compared to standard therapy alone. Researchers think lowering the level of metals found in the blood/bone marrow may help to control the disease and/or improve the response to chemotherapy.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Nowo rozpoznana białaczka ostra lub podobne nowotwory szpiku kostnego średniego lub wysokiego ryzyka
  • Wtórna białaczka ostra (rozwinęła się z innej choroby krwi)
  • Rozpoczęcie leczenia nie później niż w drugiej serii terapii
  • Dobry ogólny stan zdrowia (ocena ECOG 0-2)

✗ Disqualifies

  • Osoby poniżej 18 lat
  • Białaczka ostra całkowicie wyleczona (w pełnej remisji)
  • Pewne rzadkie podtypy białaczki ostrej (z translokacją t(8;21) lub inv(16))

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 25, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

The University of Texas M. D. Anderson Cancer Center

Houston, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/26/2026.

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