7-Days Water-Only Fasting or Ketone Supplementation Trial in Prostate Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Activating the immune system to kill cancer cells is a promising therapeutic strategy for some patients with cancer. Unfortunately, current immune-targeting treatments do not work for patients with prostate cancer. In animal models of cancer, fasting can reprogram the body's metabolism and immune cell function to help immune cells kill cancer cells likely by increasing ketosis. The purpose of this study is to determine whether 7 days of water-only fasting or a ketogenic very low-calorie diet or ketone supplementation is safe and feasible for patients with prostate cancer. This will help the investigators develop future studies to test whether incorporating periods of fasting or very low calorie diets or a ketone supplement into treatment plans for prostate cancer can improve outcomes from this disease.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjenci w dobrym ogólnym stanie zdrowia (zdolność do codziennej aktywności)
- •Wiek powyżej 18 lat
- •Potwierdzony rak prostaty
- •Zgoda na dodatkowe biopsje (jeśli konieczne)
- •Poziom PSA nie spada ostatnio
- •Wskaźnik masy ciała (BMI) między 20 a 35
- •Możliwe wcześniejsze leczenie raka prostaty (z pewnymi ograniczeniami czasowymi)
- •Dobra czynność wątroby i nerek
✗ Disqualifies
- •Pacjenci w bardzo złym stanie zdrowia (znacznie ograniczeni fizycznie)
- •Niezamierzone znaczące schudnięcie w ostatnich 3 miesiącach
- •Cukrzyca (wymagająca leczenia lub z wysokim HbA1c)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- June 30, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (1)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, United States
Trial contact
Laura Sena, MD, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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