A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The main purpose of the study is to assess the safety and tolerability of AZD2284, AZD2287, and AZD2275.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony rozpoznanie raka gruczołu krokowego bez cech przemiany neuroendokrynnej
- •Usunięcie obu jąder lub przyjmowanie leków obniżających poziom testosteronu (stan kastracjny)
- •Co najmniej jedno ognisko nowotworu w innych organach widoczne w badaniach obrazowych (CT, MRI lub scyntygrafii kostnej) wykonanych maksymalnie 28 dni przed rozpoczęciem leczenia
- •Prawidłowe funkcjonowanie wątroby, nerek i innych narządów
- •Część B: Wcześniejsze leczenie co najmniej jednym lekiem z grupy inhibitorów receptora androgenowego
- •Możliwość samodzielnego funkcjonowania lub konieczność minimalnej pomocy medycznej
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 16, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (16)
Research Site
Palo Alto, United States
Research Site
San Diego, United States
Research Site
Miami, United States
Research Site
Tampa, United States
Research Site
Chicago, United States
Research Site
Metairie, United States
Research Site
Boston, United States
Research Site
Rochester, United States
Research Site
Omaha, United States
Research Site
New York, United States
Research Site
Cleveland, United States
Research Site
Portland, United States
Research Site
East Melbourne, Australia
Research Site
CapeTown, South Africa
Research Site
Durban, South Africa
Research Site
Pretoria, South Africa
Trial contact
AstraZeneca Clinical Study Information Center
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/17/2026.
You can help another person
We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.