RecruitingEN originalColorectal cancer

Shield Post-Approval Study Protocol

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The Shield post-approval study (PAS) is a prospective, longitudinal study supplemented with Real World Evidence (RWE) to evaluate the longitudinal performance of Shield in an average risk population at a second round of testing for individuals between the ages of 45 and 81 at average risk of CRC using colonoscopy as the reference method.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek 45-81 lat
  • Chęć wykonania testu Shield jako standardowa opieka medyczna
  • Średnie ryzyko raka jelita grubego - brak objawów i dodatkowych czynników ryzyka
  • Zgoda na udział w badaniu i wykonanie badań kontrolnych

✗ Disqualifies

  • Kolonoskopia wykonywana z powodu objawów choroby
  • Historia raka jelita grubego, polipów lub innych pokrewnych nowotworów
  • Historia raka jelita grubego u pierwszego stopnia pokrewieństwa (rodzice, rodzeństwo, dzieci)
  • Pozytywny wynik innego testu przesiewowego raka jelita w ostatnich 6-36 miesięcy
  • Choroby genetyczne związane z wysokim ryzykiem raka jelita (zespół Lyncha, polipoza rodzinna i inne)
  • Pozytywny wynik testu Shield w ostatnich 3 latach
  • Historia innych nowotworów złośliwych (z wyjątkami dotyczącymi raka skóry)

Simplified criteria — AI translation

Trial details

Minimum age
45 Years
Maximum age
81 Years
Last updated (source)
August 7, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (69)

Southeast Valley Gastroenterology Consultants

Chandler, United States

Southeast Valley Gastroenterology Consultants

Gilbert, United States

Elite Primary Physicians, Inc.

Anaheim, United States

Alliance Research Institute, LLC

Canoga Park, United States

Paragon Rx Clinical, Inc.

Garden Grove, United States

Amicis Research Center

Granada Hills, United States

Desert Oasis Healthcare Medical Group

Palm Springs, United States

Amicis Research Center

Sherman Oaks, United States

Amicis Research Center

Valencia, United States

Coral Clinics

Winnetka, United States

Digestive Disease Associates

Branford, United States

Digestive Disease Associates

Branford, United States

Gastroenterology Consultants of Boca Raton, LLC

Boca Raton, United States

Manuel Espinel MD PA

Delray Beach, United States

Innova Pharma Research, LLC

Doral, United States

Marisela Gonzalez, MD

Miami, United States

Research Associates of South Florida, LLC

Miami, United States

Florida South Research Phase I-IV, Inc.

Miami, United States

Physicians Group of South Florida

North Miami, United States

NMC Research

Tampa, United States

Digestive Disease Consultants

Bourbonnais, United States

Digestive Disease Consultants

Bourbonnais, United States

Christie Clinic

Champaign, United States

Christie Clinic

Champaign, United States

GI Solutions of Illinois

Chicago, United States

GI Solutions of Illinois

Chicago, United States

Digestive Health Services

Downers Grove, United States

Digestive Health Services

Downers Grove, United States

Gastroenterology and Internal Medicine Specialists (GAIMS)

Lake Barrington, United States

Gastroenterology and Internal Medicine Specialists (GAIMS)

Lake Barrington, United States

Northshore Center for Gastroenterology (NCG)

Libertyville, United States

Southwest Gastroenterology (SWG)

Oak Lawn, United States

Southwest Gastroenterology (SWG)

Oak Lawn, United States

Hutchinson Clinic

Hutchinson, United States

Northlake Gastroenterology Associates

Covington, United States

Northlake Gastroenterology Associates

Hammond, United States

Embassy Research Network

Bloomfield Township, United States

Quinn Healthcare, PLLC

Ridgeland, United States

Gastroenterology Associates of New Jersey, LLC

Clifton, United States

Gastroenterology Associates of New Jersey

Hackensack, United States

Gastroenterology Associates of New Jersey, LLC

Montclair, United States

Gastroenterology Associates of New Jersey, LLC

Ridgewood, United States

Gastroenterology Associates of New Jersey, LLC

Wayne, United States

Gastroenterology Associates of New Jersey

Wayne, United States

Associated Gastroenterologists of Central New York

Camillus, United States

Syracuse Gastroenterological Associates, P.C.

East Syracuse, United States

Associated Gastroenterologists of Central New York

Fayetteville, United States

NYU Langone

New York, United States

Orchard Park Family Practice

Orchard Park, United States

GastroCare LI

Valley Stream, United States

GastroCare LI

Valley Stream, United States

Cary Gastroenterology Associates

Cary, United States

University of North Carolina at Chapel Hill

Chapel Hill, United States

University of North Carolina at Chapel Hill

Chapel Hill, United States

University of North Carolina at Chapel Hill

Hillsborough, United States

Piedmont Healthcare, P.A.

Mocksville, United States

Pinehurst Medical Clinic

Pinehurst, United States

Sanford Cardiology Pinehurst Medical Clinic

Sanford, United States

Piedmont Healthcare LLC

Statesville, United States

US Digestive Health at Blair

Altoona, United States

University of Pennsylvania

Philadelphia, United States

Health Living at Pottstown Medical Specialists, Inc

Pottstown, United States

Premier Family Physicians

Austin, United States

Premier Family Physicians

Austin, United States

Integrity Advanced Therapeutics, PLLC

Houston, United States

Center for Digestive Disease

Shenandoah, United States

Horizon Clinical Research Group

Tomball, United States

Horizon Clinical Research Group

Tomball, United States

Tidewater Physician Multispecialty Group Clinical Research

Williamsburg, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/8/2026.

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