RecruitingPhase IIEN originalLiver cancer

STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to compare the effects on participants' and liver cancer by adding a drug that is used on its own to treat this disease to a combination of two other drugs which is also used to treat liver cancer, compared to the two-drug combination alone.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Masa ciała powyżej 30 kg
  • Oczekiwana długość życia co najmniej 12 tygodni
  • Potwierdzony rak wątroby (badaniem tkanki lub obrazowaniem)
  • Rak wątroby, którego nie można operować
  • Brak poprzedniego leczenia systemowego tego raka
  • Dobry stan ogólny pacjenta (ECOG 0 lub 1)
  • Dobna funkcja wątroby (klasa Child-Pugh A lub B7)

✗ Disqualifies

  • Poprzednie leczenie systemowe raka wątroby
  • Kwalifikacja do leczenia lokalnego (wlewu, napromieniania)
  • Zaawansowana niewydolność wątroby (klasa Child-Pugh C)

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 14, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (12)

Arthur J.E. Child Comprehensive Cancer Centre

Calgary, Canada

BCCA - Vancouver

Vancouver, Canada

Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Canada

Kingston Health Sciences Centre

Kingston, Canada

Waterloo Regional Health Network (WRHN)

Kitchener, Canada

London Health Sciences Centre Research Inc.

London, Canada

Trillium Health Partners - Credit Valley Hospital

Mississauga, Canada

Ottawa Hospital Research Institute

Ottawa, Canada

University Health Network

Toronto, Canada

CHUM-Centre Hospitalier de l'Universite de Montreal

Montreal, Canada

The Jewish General Hospital

Montreal, Canada

Saskatoon Cancer Centre

Saskatoon, Canada

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/15/2026.

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