Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Female patients with early onset (\<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failure carries significant cardiac, musculoskeletal, sexual, and psychosocial morbidity. Ovarian transposition carries variable success rates, is not readily accessible to the general population, and can still be at risk of clinically significant radiotherapy doses. There is an unmet need for innovative techniques to protect ovarian function.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Biologiczna kobieta w wieku 18-50 lat
- •Regularny cykl miesiączkowy bez objawów menopauzy
- •Co najmniej jeden jajnik widoczny na badaniu tomograficznym lub rezonansem magnetycznym
- •Planowana radioterapia z powodu choroby nowotworowej
- •Zdolność zrozumienia badania i chęć podpisania zgody
✗ Disqualifies
- •Poprzednia radioterapia miednicy
- •Poprzednie leczenie nowotworów wpływające na jajniki
- •Wcześniejsza diagnoza niewydolności jajników lub menopauza
- •Objawy menopauzy (uderzenia gorąca, nieregularny cykl)
- •Jajniki operacyjnie usunięte lub przesadzone
- •Ciąża lub karmienie piersią
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 50 Years
- Last updated (source)
- September 2, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (1)
Washington University School of Medicine
St Louis, United States
Trial contact
Michael Waters, M.D., Ph.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/3/2026.
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