Organoid Models of Hepatocellular Carcinoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
A promising tool to elucidate the molecular characteristics of HCC are patient-derived organoids (PDOs), three-dimensional cultures of cells that self-organise according to tissue-specific patterns and can be used to test the susceptibility of a specific tumour to anticancer agents. In this study, PDOs for HCC will be developed that closely resemble the tumour microenvironment in vivo and mimic the crosstalk of the gut-liver axis to establish a correlation with patient prognosis and test the efficacy of available systemic therapies.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Podejrzenie raka wątroby potwierdzone badaniami obrazowymi lub potwierdzony rozpoznaniem raka wątroby kwalifikujący się do operacji
- •Zdolność do wyrażenia świadomej zgody na udział w badaniu
✗ Disqualifies
- •Wiek poniżej 18 lat
- •Przeciwwskazania do pobrania próbki wątroby (nagromadzenie płynu w brzuchu, zbyt mało płytek krwi, zaburzona krzepliwość krwi)
- •Przeciwwskazania do operacji usunięcia raka wątroby
- •Aktywne zakażenie wirusowe
- •Brak zgody na uczestnictwo w badaniu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 21, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC CEMAD, Largo A. Gemelli, 8
Roma, Italy
Trial contact
Francesca Romana Ponziani, PI
Elisabetta Creta, SC
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/22/2026.
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