Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This clinical trial studies whether a new multi-layer perinatal tissue allograft, MLG-Complete (Trademark), can be used to improve complications after nerve-sparing robot-assisted radical prostatectomy (RARP) in patients with prostate cancer that has not spread to other parts of the body (localized). Two major complications that can happen after complete surgical removal of the prostate (radical prostatectomy) include erectile dysfunction and urinary incontinence, both of which greatly affect a patient's quality of life and social well-being. The goal of nerve-sparing radical prostatectomy is to preserve erectile and urinary function, but damage to the surrounding nerves and blood vessels can still occur causing the patient to experience the complications. An allograft is the transplant of an organ, tissue, or cells from one individual to another individual of the same species who is not an identical twin. The MLG-Complete allograft is made up of perinatal tissue and is placed on the nerve bundles during a nerve-sparing RARP. It is meant to serve as a barrier and provide coverage to the nerve bundles from the surrounding environment, which may improve post-nerve-sparing RARP complications.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Mężczyzna w wieku 45 lat lub starszy
- •Rozpoznany rak prostaty, który nie rozprzestrzeniał się na inne narządy
- •Zaplanowana operacja usunięcia prostaty z próbą zachowania nerwów
- •Brak problemów z potencją przed operacją
- •Zainteresowanie utrzymaniem zdolności do współżycia seksualnego
- •Gotowość do uczestnictwa w badaniu i wizytach kontrolnych
- •Zdolność do wyrażenia pisemnej zgody
✗ Disqualifies
- •Agresywny rak prostaty wymagający dodatkowego leczenia
- •Niemożliwość uczestnictwa w programie rehabilitacji potencji
- •Stosowanie leków immunosupresyjnych w ciągu ostatniego miesiąca
- •Wcześniejsze leczenie hormonalne lub radioterapia miednicy
- •Poważne problemy z kontrolą moczu wymagające użycia pieluszek
- •Otyłość (BMI powyżej 40)
- •Planowana chemioterapia, radioterapia lub inne operacje podczas badania
Simplified criteria — AI translation
Trial details
- Minimum age
- 45 Years
- Last updated (source)
- August 17, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (1)
Mayo Clinic in Florida
Jacksonville, United States
Trial contact
Clinical Trials Referral Office
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/6/2026.
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