Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Pilot study to determine feasibility of adding intrathecal chemotherapy and maintenance therapy after high dose chemotherapy for treatment of newly diagnosed HR-EBTs in patients less than 6 years of age.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek: dziecko musi mieć od 0 do 6 lat w momencie postawienia diagnozy
- •Potwierdzony nowotwór mózgu, np. guz ATRT, medulloblastoma, pineoblastoma lub inne embryonalne nowotwory mózgu
- •Próbka tkanki potwierdzająca rozpoznanie
- •Badania MRI mózgu i kręgosłupa przed i po operacji
- •Spodziewana przeżywalność co najmniej 8 tygodni od diagnozy
- •Stan ogólny dziecka pozwalający na leczenie (skala Lansky'ego ≥ 50 punktów)
- •Prawidłowe funkcjonowanie nerek, serca i płuc
Simplified criteria — AI translation
Trial details
- Maximum age
- 6 Years
- Last updated (source)
- July 14, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (12)
Alberta Children's Hospital
Calgary, Canada
BC Children's Hospital
Vancouver, Canada
CancerCare Manitoba (CCMB)
Winnipeg, Canada
IWK Health Centre
Halifax, Canada
McMaster Children's Hospital
Hamilton, Canada
London Health Sciences Centre
London, Canada
CHU Sainte-Justine
Montreal, Canada
Montreal Children's Hospital (McGill)
Montreal, Canada
CHU de Québec-Université Laval
Québec, Canada
Centre hospitalier universitaire de Sherbrooke (CHUS)
Sherbrooke, Canada
Stollery Children's Hospital
Edmonton, Canada
The Hospital for Sick Children
Toronto, Canada
Trial contact
Sylvia Cheng
C17 Council
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/15/2026.
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