Boron Neutron Capture Therapy With B10 L-BPA for Unresectable Recurrent Head and Neck Cancers
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This Phase II study, titled "A Phase II Study to Evaluate the Efficacy and Safety of Boron Neutron Capture Therapy (BNCT) Using B10 L-BPA in Patients with Unresectable Recurrent Head and Neck Cancers," aims to assess the efficacy and safety of B10 L-BPA-based BNCT in this patient population. The primary objective is to evaluate its efficacy, while secondary objectives include assessing safety, survival outcomes, tumor response, and the pharmacokinetics (PK) profile of B10 L-BPA and boron.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18-80 lat
- •Potwierdzony rozpoznaniem raka głowy i szyi, bez przerzutów odległych
- •Nowotwór nawracający lub utrwalony po wcześniejszym leczeniu (chemio-radiacja, chemioterapia lub radiacja), którego nie można operacyjnie usunąć
- •Pacjent nienadający się do systemowego leczenia lekami lub odmawiający takiego leczenia
- •Poprzednia radiacja w zakresie 40-75 Gray w miejscu choroby
- •Co najmniej 3 miesiące od poprzedniej radiacji do planowanego leczenia
- •Mierzalna choroba na MRI lub CT, wielkość do 7 cm
- •Ogólny stan zdrowia pozwalający na uczestnictwo w badaniu (ECOG 0-2)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 80 Years
- Last updated (source)
- August 28, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (3)
Buddhist Tzu Chi Medical Foundation, Dalin Tzu Chi Hospital
Chiayi City, Taiwan
China Medical University Hospital
Taichung, Taiwan
Taipei Veterans General Hsopital, Taipei,
Taipei, Taiwan
Trial contact
Hung Shih-Kai Principal Investigator
Chao Kun-San Principal Investigator
Wang Ling-Wei Principal Investigator
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/29/2026.
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