RecruitingPhase IIEN originalLiver cancer

Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to evaluate the impact of iparomlimab and tuvonralimab as preoperative neoadjuvant therapy on recurrence-free survival (RFS), along with its potential improvement in overall survival (OS), in patients with resectable hepatocellular carcinoma (HCC) at high risk of recurrence.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Potwierdzony rak wątroby (biopsja lub badania obrazowe)
  • •Wiek od 18 do 75 lat
  • •Tumor można całkowicie usunąć chirurgicznie
  • •Brak przerzutów w innych organach
  • •Wcześniej nie leczono lekami ukierunkowanymi na raka wątroby
  • •Wystarczająca funkcja wątroby, nerek i krwi
  • •Spodziewana życliność co najmniej 12 tygodni
  • •Wysoki risk nawrotu: wiele guzów lub wznowienie się w naczyniach żylnych

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
75 Years
Last updated (source)
September 18, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/19/2026.

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