Investigating Multigene Methylation Dynamics in Treatment Response Surveillance for Gastric Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The primary objective is to determine whether pretreatment-to-posttreatment changes in circulating multigene methylation levels correlate with objective response rates (ORR) assessed by contrast-enhanced CT/MRI and levels of serum tumor markers. Secondary endpoints include: (a) time-dependent association between methylation fluctuation patterns and progression-free survival (PFS), (b) comparative diagnostic accuracy of methylation indices versus conventional biomarkers, and (c) feasibility of using methylation thresholds to guide adaptive therapy modification.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18-75 lat w momencie rozpoznania
- •Potwierdzony nowotwór żołądka lub połączenia żołądka z przełykiem
- •Brak innych nowotworów w przeszłości
- •Brak przerzutów do wątroby, płuc lub innych miejsc
- •Bez wcześniejszego leczenia operacyjnego, chemioterapii lub immunoterapii
- •Dostępne pełne dane medyczne i wyniki badań
✗ Disqualifies
- •Oczekiwana długość życia poniżej 6 miesięcy
- •Poważne zaburzenia psychiczne lub demencja
- •Osoby ubezwłasnowolnione bez opiekuna prawnego
- •Inne powody uznane przez lekarza prowadzącego badanie
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 75 Years
- Last updated (source)
- August 27, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (2)
Tangdu Hospital
Xi'an, China
Xijing Hospital
Xi'an, China
Trial contact
Zhongyang Zhang
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/28/2026.
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