Reducing Symptom Burden Through Physical Exercise in Melanoma Patients
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The aim of the clinical trial is to determine whether regular exercise can reduce fatigue in adult patients with stage IIb-IV melanoma undergoing immunotherapy or targeted therapy. Additionally, we will investigate whether a supervised exercise program improves patients' quality of life, cognitive skills, and physical fitness compared to a control group without structured exercise. We will also examine other health outcomes and various blood parameters, such as interleukins and metabolites, to understand how regular activity can affect metabolism and immune function. After the initial assessment at the clinic, patients will be randomly assigned to two groups. Those in the intervention group will participate in a 12-week exercise program, which includes a 60-minute personalized and supervised online training session twice a week. In weeks 3, 6, and 9, one training session will be held at the clinic. Furthermore, patients in the intervention group are encouraged to complete a self-administered 20-minute exercise session once a week. The control group will not receive a supervised exercise program. Following the 12-week intervention period, another assessment will be conducted at the clinic. All patients will then enter a 6-week follow-up phase, during which neither group will receive supervised exercise training. After this follow-up phase, a final assessment of all outcomes will take place at the clinic.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat z potwierdzonym czerniakiem (stadium IIb-IV)
- •Obecnie leczenie immunoterapią lub terapią celowaną
- •Leczenie tym samym schematem od 3 do 9 miesięcy
- •Zdolność do uczestniczenia w programie ćwiczeń
- •Pozwolenie lekarza na uczestniczenie w ćwiczeniach i testach
- •Możliwość regularnych wizyt w szpitalu na zajęcia i badania
- •Podpisana zgoda na uczestniczenie w badaniu
✗ Disqualifies
- •Lekarz stwierdził przeciwwskazania do ćwiczeń (np. wysoki risk złamań kości)
- •Nieprawidłowo leczeni przerzuty do mózgu powodujące objawy
- •Poważne zaburzenia serca lub układu nerwowego
- •Poważne problemy z oddychaniem
- •Spodziewana długość życia poniżej 3 miesięcy
- •Bardzo intensywna aktywność fizyczna (powyżej 150 minut tygodniowo)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 8, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
University Hospital Essen
Essen, Germany
Trial contact
Simon Basteck, M.Sc.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/9/2026.
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