RecruitingPhase IIEN original

Glofitamab, Polatuzumab Vedotin and Zanubrutinib in First-line Elderly DLBCL

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study aims to assess the efficacy and safety of the chemotherapy-light combination of glofitamab, polatuzumab vedotin and zanubrutinib (GPZ) in elderly patients with previously untreated diffuse large B-cell lymphoma.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek 70 lat lub więcej
  • •Potwierdzony rozpoznaniem chłoniaka z dużych komórek B typu CD20-dodatni
  • •Chłoniak poddający się pomiarowi w badaniach obrazowych
  • •Brak wcześniejszego leczenia chłoniaka
  • •Spodziewana długość życia co najmniej 12 tygodni
  • •Prawidłowa praca wątroby i nerek
  • •Prawidłowe wyniki badań krwi (hemoglobina, neutrofile, płytki)
  • •Pisemna zgoda na udział w badaniu

✗ Disqualifies

  • •Poważne choroby serca w ostatnich 3 miesiącach (zawał, udar, zaburzenia rytmu)
  • •Wysoki stopień niewydolności serca

Simplified criteria — AI translation

Trial details

Minimum age
70 Years
Last updated (source)
October 16, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Zhongshan Hospital, Fudan University

Shanghai, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/17/2026.

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