Prospective External Control Cohort In Patients With Newly Diagnosed Advanced or Metastatic EGFR Mutant Non-Small Cell Lung Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The objective of this study is to build a prospective cohort in patients with locally advanced or metastatic NSCLC with common EGFR mutations. In NPM-002, there will be standardized data collection at baseline, on-treatment and at discontinuation of therapy. Patients who enroll prior to initiation of osimertinib treatment (\~30%) will undergo imaging with standardized intervals.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Potwierdzony zaawansowany rak płuc z mutacją EGFR (typ exon 19 lub exon 21)
  • Nowa diagnoza od stycznia 2024 roku

✗ Disqualifies

  • Zły ogólny stan zdrowia (wynik ECOG 2 lub więcej)
  • Wcześniejsze leczenie lekami: osimertinib, amivantamab lub lazertinib

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 16, 2026
Sex
No restrictions

Locations (9)

Pacific Cancer Care

Monterey, United States

Torrance Memorial Physician Network-Cancer Care

Torrance, United States

John Muir Health

Walnut Creek, United States

Bayhealth Cancer Center- Kent

Dover, United States

Bayhealth Cancer Center- Sussex

Milford, United States

Kootenai Clinic Cancer Services Coeur d'Alene

Coeur d'Alene, United States

Northwest Oncology & Hematology

Elk Grove Village, United States

Lankenau Medical Center

Paoli, United States

Oncology Consultants, P.A.

Houston, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/17/2026.

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