TQB2930 Injection for the Treatment of HER2-positive Advanced Breast Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
TQB2930 is a HER2 bispecific antibody drug. This study aims to evaluate the efficacy and safety of TQB2930 combined with investigator's choice of chemotherapy versus trastuzumab combined with investigator's choice of chemotherapy in subjects with HER2-positive advanced breast cancer who have received at least two prior lines of anti-HER2 therapy in the advanced station.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjent wyraża zgodę na udział i podpisuje formularz świadomej zgody.
- •Wiek od 18 do 75 lat, ogólny stan zdrowia pozwalający na normalną aktywność.
- •Zdiagnozowany rak piersi HER2-dodatni, który powrócił lub jest w stadium zaawansowanym/przerzutowym.
- •Przed leczeniem otrzymano co najmniej dwie różne terapie skierowane przeciwko HER2 w leczeniu zaawansowanej choroby.
- •Obecność przynajmniej jednej zmiany widocznej w badaniach obrazowych.
- •Zgoda na otrzymanie jednego z wybranych przez lekarza schematów chemioterapii.
- •Dobre wyniki badań wskazujące na prawidłowe funkcjonowanie narządów.
- •Kobiety w wieku rozrodczym muszą stosować skuteczną antykoncepcję.
✗ Disqualifies
- •Inne choroby nowotworowe w ciągu ostatnich 5 lat (z pewnymi wyjątkami).
- •Niewyleczone powikłania po wcześniejszym leczeniu (poza utratą włosów).
- •Ważne zabiegi chirurgiczne lub urazy w ciągu ostatnich 28 dni.
- •Niewyleczone rany lub złamania.
- •Zakrzepica lub zatorowość w ciągu ostatnich 6 miesięcy.
- •Problemy z sercem, takie jak zawał, zaburzenia rytmu lub niewydolność serca.
- •Aktywne lub niekontrolowane poważne infekcje.
- •Ciężkie, niekontrolowane nadciśnienie tętnicze.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 75 Years
- Last updated (source)
- June 3, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (75)
The First Affiliated Hospital of Bengbu Medical College
Bengbu, China
Anhui Provincial Hospital( The First Affiliated Hospital of USTC)
Hefei, China
The Second Affiliated Hospital of Anhui Medical University
Hefei, China
The Fifth Medical Center of Chinese People's Liberation Army General Hospital
Beijing, China
Chong Qing University Cancer Hospital
Chongqing, China
Fuzhou First Generel Hospital Affiliated with Fujian Medical University
Fuzhou, China
The First Hospital of Lanzhou University
Lanzhou, China
Gansu Cancer Hospital
Lanzhou, China
Sun Yat - sen University Cancer Center
Guangzhou, China
Peking University Shenzhen Hospital
Shenzhen, China
The Second Affiliated Hospital of Guangxi University of Science and Technology
Liuzhou, China
Liuzhou People's Hospital
Liuzhou, China
Affiliated Cancer Hospital of Guangxi Medical Universit
Nanning, China
The Affiiated Cancer Hospital of Guizhou Medical University
Guiyang, China
Guizhou Provincial People's Hospital
Guiyang, China
Hainan General Hospital
Haikou, China
The First Hospital of Qinhuangdao
Qinhuangdao, China
The Fourth Hospital of Hebei Medical University
Shijiazhuang, China
Tangshan People's Hospital
Tangshan, China
Harbin Medical University Cancer Hospital
Harbin, China
The First Affiliated Hospital of Harbin Medical University
Harbin, China
Jiamusi Tuberculosis Hospital (Jiamusi Tumor Hospital)
Jiamusi, China
Mudanjiang Cancer Hospital
Mudanjiang, China
AnYang Tumor Hospital
Anyang, China
The First Affiliated Hospital of Henan University of Science & Technology
Luoyang, China
Nanyang Second General Hospital
Nanyang, China
The First Affiliated Hospital of Xinxiang Medical University
Xinxiang, China
Henan Cancer Hospital
Zhengzhou, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, China
Jingmen People's Hospital
Jingmen, China
Xiangyang Central Hospital
Xiangyang, China
The First People's Hospital of Changde City
Changde, China
Hunan Cancer Hospital
Changsha, China
People's Hospital of Hunan Province
Changsha, China
Xiangya Hospital of Central South University
Changsha, China
The Central Hospital of Yongzhou
Yongzhou, China
Zhangjiajie People's Hospital
Zhangjiajie, China
JiangSu Cancer Hosipital
Nanjing, China
The Affiliated Sir Run Run Hospital of Nanjing Medical University
Nanjing, China
Nanjing Drum Tower Hospital
Nanjing, China
Zhangjiagang First People's Hospital
Suzhou, China
Xuzhou Central Hospital
Xuzhou, China
Ganzhou Cancer Hospital
Ganzhou, China
Ganzhou People's Hospital
Ganzhou, China
Jiangxi Cancer Hospital
Nanchang, China
Jilin Cancer Hospital
Changchun, China
The first hospital of Jilin University
Changchun, China
Affiliated Zhongshan Hospital Of Dalian University
Dalian, China
Shengjing Hospital of China Medical University
Shenyang, China
Liaoning Cancer Hospital & Institute
Shenyang, China
People's Hospital of Ningxia Hui Autonomous Region
Yinchuan, China
Qinghai University Affiliated Hospital
Xining, China
Bao Ji Central Hospital
Baoji, China
3201 Hospital
Hanzhong, China
The Second Affiliated Hospital Of Xi'an Jiaotong University (Xibei Hospital)
Xi'an, China
Xijing Hospital of Air Force Military Medical University
Xi'an, China
Shandong Provincial Hospital Affiliated to Shandong First Medical University（Shandong Provincial Hospital）
Jinan, China
Cancer Hospital of Shandong First Medical University (Shandong Cancer Institute,Shandong Cancer Hospital)
Jinan, China
Linyi cancer Hospital
Linyi, China
Weifang People'S Hospital
Weifang, China
Shanxi Cancer Hospital
Taiyuan, China
Yuncheng Central Hospital
Yuncheng, China
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Chengdu, China
The Affiliated Hospital of Southwest Medical University
Luzhou, China
Affiliated Hospital of North Sichuan Medical College
Nanchong, China
Suining Central Hospital
Suining, China
The Second People's Hospital of Yibin City
Yibin, China
Tianjin Medical University Cancer Institute & Hospital
Tianjin, China
Tianjin Cancer Hospital Airport Hospital
Tianjin, China
Xinjiang Medical University Affiliated Tumor Hospital
Ürümqi, China
Yunnan Cancer Hospital
Kunming, China
Ningbo Medical Center Lihuili Hospital
Ningbo, China
Ningbono.2Hospitai
Ningbo, China
The First Affiliated Hospial of Ningbo University
Ningbo, China
The Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, China
Trial contact
Qingyuan Zhang, Doctor
Jinming Yu, Doctor
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.
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