Prevalence and Predictors of Incidental Thyroid Carcinoma in Patients With Graves' Disease Undergoing Thyroidectomy.
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The prevalence of incidental thyroid cancer (ITC) in Graves' Disease (GD) patients undergoing thyroidectomy appears higher than historically believed, potentially exceeding 10% in large contemporary series, although significant variability exists. The presence of nodules is a strong predictor, while the roles of age, sex, and BMI require clarification. Most ITCs are papillary thyroid microcarcinoma(PTMCs) with generally favorable prognoses, but concerns about aggressiveness persist. The purpose of the present study is to accurately evaluate the prevalence of incidental thyroid carcinoma (ITC), including microcarcinomas, in a prospectively enrolled cohort of patients undergoing total thyroidectomy for Graves' disease, utilizing standardized pathological examination protocols and secondary outcomes including predictors and histopathological characteristics.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Potwierdzona diagnoza choroby Gravesa (rozszerzona tarcza i/lub podwyższone hormony tarczycy)
- •Zaplanowana operacja usunięcia całej tarczycy z powodu choroby Gravesa
- •Chęć i zdolność do podpisania świadomej zgody na uczestnictwo w badaniu
- •Możliwość zrozumienia procedur i wymagań badania
✗ Disqualifies
- •Wiek poniżej 18 lat
- •Wcześniejsza operacja na tarczycy
- •Wcześniejsze napromienianie szyi
- •Już potwierdzony rak tarczycy przed operacją
- •Niemożność podpisania zgody na uczestnictwo
- •Operacja planowana z innych powodów niż choroba Gravesa
- •Planowana operacja częściowa lub prawie całkowita, a nie całkowita
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 75 Years
- Last updated (source)
- August 11, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Minia University Hospital
Minya, Egypt
Trial contact
Saleh K Saleh, MD
Rabeh K Saleh, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/12/2026.
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