A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to find out whether the combination of epcoritamab and ibrutinib is a safe treatment approach that causes few or mild side effects in people with relapsed/refractory primary central nervous system lymphoma (PCNSL) or secondary central nervous system lymphoma (SCNSL).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzony chłoniak typu DLBCL (poprzez biopsję lub pobranie płynu)
- •Stan ogólny organizmu pozwalający na aktywność codzienną (ECOG 0-2)
- •Wystarczająca funkcja szpiku kostnego i narządów wewnętrznych
- •Liczba płytek krwi powyżej 75 miliardów na litr
- •Hemoglobina powyżej 8 g/dL
- •Prawidłowa funkcja wątroby i nerek
- •Kobiety w wieku rozrodczym muszą stosować antykoncepcję przez czas leczenia i 30 dni po
✗ Disqualifies
- •Chłoniak po raz pierwszy zdiagnozowany (nowy)
- •Chłoniak poza ośrodkowym układem nerwowym
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 14, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (8)
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, United States
University of Utah (Data Collection Only)
Salt Lake City, United States
Trial contact
Christian Grommes, MD
Lauren Schaff, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/15/2026.
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