RecruitingPhase IIMale onlyEN originalProstate cancerMetastatic / advanced

A Study of Tarlatamab for People With Prostate Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The researchers are doing this study to find out whether tarlatamab is an effective treatment for Delta-like Protein 3 (DLL3)-positive prostate cancer that has spread to other parts of your body (metastasized) and has either come back after treatment (relapsed) or not responded to treatment (refractory).

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek 18 lat lub więcej
  • •Potwierdzony rozpoznaniem raka prostaty
  • •Rak rozprzestrzenił się na inne części ciała (widoczny w badaniach CT, MRI lub scyntygrafii kości)
  • •Poziom testosteronu poniżej 50 ng/dL lub podjęcie odpowiedniego leczenia hormonalnego
  • •Pogorszenie stanu pomimo wcześniejszego leczenia (widoczne w podwyższonym PSA, wzroście guzów lub nowych zmianach w kościach)
  • •Zdolność do wyrażenia świadomej zgody na uczestnictwo w badaniu
  • •Saturacja tlenu w spoczynku co najmniej 90% na powietrzu pokojowym

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 31, 2026
Sex
Male only

Therapies / drugs in trial

Locations (10)

UNIVERSITY OF CALIFORNIA SAN DIEGO (Data collection only)

San Diego, United States

University of California San Francisco

San Francisco, United States

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Basking Ridge, United States

Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Middletown, United States

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Montvale, United States

Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

Commack, United States

Memorial Sloan Kettering Westchester (Limited Protocol Activities)

Harrison, United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, United States

Memorial Sloan Kettering Nassau (Limited Protocol Activities)

Uniondale, United States

Thomas Jefferson University Hospital

Philadelphia, United States

Trial contact

Michael Morris, MD

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/1/2026.

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