Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this study is to evaluate the feasibility and effectiveness of same-day radiation planning and treatment. The study will shorten the time interval between radiation planning (radiation mapping) and radiation treatment. The intent of this shorter time interval is to increase the likelihood that the brain metastases being treated remain fully within the high-dose radiation fields. Participants will be randomized to receive brain-directed stereotactic radiation with a 1mm margin or 0mm margin, have their simulation/radiation planning imaging on the same day that brain-directed stereotactic radiation is delivered, and have repeat simulation/radiation planning scans during the course of treatment if more than 2-3 days have elapsed since the most recent scans.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony nowotwór złośliwy z co najmniej jednym przerzutem do mózgu
- •Przerzut rozwija się szybko - przybywa co najmniej 1 mm tygodniowo
- •Wiek co najmniej 18 lat
- •Ogólny stan zdrowia wystarczający do leczenia (Karnofsky co najmniej 60)
- •Oczekiwana przeżywalność co najmniej 3-6 miesięcy
- •Zgodność na udział w badaniu
✗ Disqualifies
- •Niemożliwość wykonania rezonansu magnetycznego mózgu
- •Alergia na środek kontrastowy gadolin
- •Ciężka choroba nerek
- •Rozległa choroba opon mózgowo-rdzeniowej
- •Ciąża lub karmienie piersią
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 8, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
Brigham and Women's Hospital / Dana-Farber Cancer Institute
Boston, United States
Trial contact
Ayal A Aizer, MD, MHS
Marciana F Johnson, MPH
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/9/2026.
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