Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This clinical trial evaluates the effects a probiotic intervention has on the gut and vaginal microbiome in patients undergoing chemotherapy for ovarian cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) or that has come back after a period of improvement (recurrent). Gut health is also known as the gut microbiome. The microbiome includes all of the bacteria and organisms naturally found in the digestive tract. Probiotics are dietary supplements containing live microorganisms that may help keep the gastrointestinal tract healthy. A probiotic intervention during platinum chemotherapy in ovarian cancer patients may impact the gut and vaginal microbiota, quality of life, symptoms, and oncologic outcomes.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek powyżej 18 lat
- •Rozpoznany zaawansowany (stadium II, III lub IV) lub nawrotowy rak jajnika, który będzie leczony chemioterapią zawierającą platynę
- •Gotowość uczestniczyć we wszystkich badaniach przewidzianych w studium
- •Zgoda na niestosowanie innych suplementów probiotycznych poza badaniem przez czas trwania studium
- •Gotowość do nie wprowadzania znaczących zmian w diecie podczas badania
- •Zdolność do zrozumienia i podpisania zgody na udział w badaniu
✗ Disqualifies
- •Alergiczne reaktivności na jakikolwiek składnik suplementu probiotycznego
- •Przewlekłe zapalenie lub strukturalne zaburzenia przewodu trawiennego (zapalenie jelit, wrzody, niedrożność jelit)
- •Niewystarczające wyniki badań laboratoryjnych do rozpoczęcia chemioterapii
- •Uczulenie na którykolwiek ze składników produktu badanego (bakterie, inulina, barwniki)
- •Potwierdzony rak z granic niejasnych
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 17, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (1)
Ohio State University Comprehensive Cancer Center
Columbus, United States
Trial contact
The Ohio State University Comprehensive Cancer Center
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/18/2026.
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