Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The primary objectives are to determine the recommended Phase 2 dose (RP2D) and optimal treatment regimen, characterize safety and tolerability, and evaluate preliminary efficacy of RYZ401 in subjects with NETs and other selected solid tumors expressing SSTRs.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Potwierdzony histologicznie neuroendokrynny nowotwór (stopnie 1-3) rozprzestrzeniający się lub nieoperacyjny
- •Nowotwór z obszaru żołądka, jelit lub trzustki (grupa A)
- •Inne nowotwory o receptorach somatostatyny - płuco, tarczyca, pierś, narządy płciowe, nadnercze lub oponiak (grupa B)
- •Potwierdzenie receptorów somatostatyny badaniem obrazowym PET
- •Prawidłowa funkcja nerek, wątroby i morfologia krwi
✗ Disqualifies
- •Wcześniejsze leczenie radioaktywnymi peptydami (Lu-177 lub inne)
- •Wcześniejszy przeszczep narządu lub szpiku
- •Przewlekłe stosowanie sterydów
- •Poważne choroby serca
- •Oporna na leczenie nadciśnienie tętnicze
- •Niekontrolowana cukrzyca
- •Historia marskości wątroby
- •Infekcja HIV, zapalenie wątroby typu B lub C
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 15, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (14)
Research Facility
Phoenix, United States
Research Facility
Jacksonville, United States
Research Facility
Iowa City, United States
Research Facility
Lexington, United States
Research Facility
Rochester, United States
Research Facility
St Louis, United States
Research Facility
St Louis, United States
Research Facility
Columbus, United States
Research Facility
Portland, United States
Research Facility
Nashville, United States
Research Facility
Salt Lake City, United States
Research Facility
Charlottesville, United States
Research Facility
Toronto, Canada
Research Facility
Montreal, Canada
Trial contact
RayzeBio Clinical Trials
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/16/2026.
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