RecruitingPhase I/IIEN originalLung cancerOther cancersMetastatic / advanced

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is Phase 1/2, multicenter, clinical study to evaluate the safety, efficacy, PK, and immunogenicity of IDE849 in subjects with DLL3-expressing tumors including SCLC.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Chęć udziału w badaniu i podpisanie zgody
  • Potwierdzony histologicznie lub cytologicznie rak płuca typu drobnokomórkowego lub inny nowotwór neuroendokrynny z markerem DLL3
  • Nowotwór pogorszył się lub wrócił po poprzednim leczeniu standardowym
  • Co najmniej jeden guz widoczny na badaniach obrazowych
  • Ogólny stan zdrowia pozwalający na uczestnictwo (skala ECOG 0-1)
  • Spodziewana długość życia ponad 3 miesiące
  • Prawidłowe wyniki badań krwi i funkcji narządów
  • Gotowość do pobrania próbek krwi i tkanki guza do badań

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 9, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (13)

Sarah Cannon Research Institute at HealthONE

Denver, United States

Sarah Cannon Research Institute at Florida Cancer Specialists

Orlando, United States

Fort Wayne Medical Oncology and Hematology, Inc. - Fort Wayne North Office

Fort Wayne, United States

START Midwest

Grand Rapids, United States

The Cancer and Hematology Centers

Grand Rapids, United States

Columbia University Medical Center - Herbert Irving Pavilion

New York, United States

Sidney Kimmel Cancer Center at Thomas Jefferson University

Philadelphia, United States

Sarah Cannon Research Institute - Oncology Partners

Nashville, United States

The University of Texas MD Anderson Cancer Center

Houston, United States

Oncology Consultants, PA- Houston

Houston, United States

Next Oncology Dallas

Irving, United States

NEXT Oncology Virginia

Fairfax, United States

Swedish Cancer Institute

Seattle, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.

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