A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The main goal of this study is to evaluate the safety of BNT329 and to identify the best dose of BNT329. This will be done by measuring the number of side effects that participants experience and how severe they are. The second goal of this study is to evaluate how well BNT329 works. This will be done by measuring the number of participants who respond to the treatment. The length of time where the tumor does not grow or spread will also be measured. The study will also evaluate how BNT329 moves into, through, and out of the body and how the treatment affects the body.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Zaawansowany nowotwór (rozprzestrzeniający się), który wykazuje marker CA19-9
- •Możliwość zmierzenia zmian w guzie według standardowych kryteriów medycznych
- •Oczekiwana długość życia co najmniej 3 miesiące
- •Dobre funkcjonowanie narządów wewnętrznych i zdolność krwi do krzepnięcia
- •Wcześniej otrzymane wszystkie dostępne standardowe leki przeciwnowotworowe bez efektu
✗ Disqualifies
- •Uczestnictwo w innym badaniu klinicznym w tym samym czasie
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 17, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (16)
SCRI at HCA Health One
Denver, United States
Florida Cancer Specialists
Orlando, United States
Memorial Sloan Kettering Cancer Center
New York, United States
Monash Health
Clayton, Australia
Austin Health
Heidelberg, Australia
St. Josef-Hospital im Katholischen Klinikum Bochum
Bochum, Germany
Universitaetsklinikum Ulm
Ulm, Germany
Hospital Universitari Vall d'Hebron
Barcelona, Spain
Hospital San Pedro
Logroño, Spain
Hospital Universitario HM Sanchinarro - START Madrid CIOCC
Madrid, Spain
Hospital Universitario Quironsalud Madrid - NEXT Oncology
Pozuelo de Alarcón, Spain
St James´s University Hospital
Leeds, United Kingdom
Royal Free Hospital
London, United Kingdom
The Christie NHS Foundation Trust
Manchester, United Kingdom
Northern Centre for Cancer Research
Newcastle upon Tyne, United Kingdom
The Royal Marsden Hospital
Sutton, United Kingdom
Trial contact
BioNTech clinical trials patient information
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/18/2026.
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