Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this study is to find out if self-collected vaginal swabs can be used to detect early signs of uterine cancer or related conditions in people with Lynch syndrome (LS) who still have their uterus. The study also tests if people with LS are willing and able to collect these samples themselves and whether they find the process acceptable. The main questions this study asks are: * Will people with LS take part in self-collection of vaginal samples, and do they find it acceptable? * Can vaginal DNA mutations predict cancer risk or match results from other genetic or biopsy testing? * Can a cancer risk model used in the general population also help identify risk in people with LS? Participants will: * Answer a health questionnaire about lifestyle and symptoms * Collect their own vaginal swabs and measure their vaginal pH at home using a self-collection kit * Complete short surveys around the time of self-collection and at the end of the study
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Postawiona diagnoza zespołu Lyncha (potwierdzona badaniem genetycznym)
- •Posiadanie macicy
- •Wiek 30 lat lub więcej
✗ Disqualifies
- •Historia raka lub rozrostu błony śluzowej macicy
- •Historia napromieniania miednicy lub zabiegu ablacji
- •Ciąża w momencie rozpoczęcia badania lub podczas badania
Simplified criteria — AI translation
Trial details
- Minimum age
- 30 Years
- Last updated (source)
- September 3, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (1)
VGH Research Pavilion
Vancouver, Canada
Trial contact
Aline Talhouk, PhD
Research Assistant
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/4/2026.
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