RecruitingPhase IIEN originalLiver cancer

GKL-006 Injection Plus TACE Versus TACE Alone in Patients With Unresectable Hepatocellular Carcinoma

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a multicenter, randomized, open-label, controlled Phase 2 study in patients with unresectable hepatocellular carcinoma (uHCC). The purpose of this study is to compare the efficacy and safety of GKL-006 Injection in combination with transarterial chemoembolization (TACE) versus TACE alone.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek od 18 do 80 lat
  • Potwierdzony rak wątroby, którego nie można operacyjnie usunąć
  • Co najmniej jeden widoczny na badaniach guz
  • Dobra funkcja wątroby (klasa Child-Pugh A lub B)
  • Dobne wyniki badań krwi i funkcji narządów
  • Dobry stan ogólny (ECOG 0-2)
  • Dobrowolna zgoda na udział w badaniu

✗ Disqualifies

  • Alergia na lek badawczy, albuminy lub IL-2
  • Inny nieuleczalny nowotwór w ciągu ostatnich 5 lat
  • Leczenie guza w ciągu ostatnich 12 tygodni
  • Encefalopatia wątrobowa w ciągu ostatnich 4 tygodni
  • Zbiorniki płynu w brzuchu lub płucach wymagające drażenia
  • Inne aktywne choroby zagrażające zdrowiu

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
80 Years
Last updated (source)
August 17, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (7)

302 Hospital

Beijing, China

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China

The Second Xiangya Hospital of Central South University

Changsha, China

Zhongda Hospital

Nanjing, China

Nanjing Second Hospital

Nanjing, China

Jiangxi Cancer Hospital

Nanchang, China

Zhejiang Cancer Hospital

Hangzhou, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/18/2026.

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