A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This global, open-label, single arm, phase 1b study aims to learn more about whether a treatment called JNJ-90301900 is safe and effective when injected directly into tumors, along with standard chemotherapy and radiation therapy, for participants with head and neck squamous cell cancer (HNSCC; a type of solid tumor that begins in outer tissue layer of the mouth \& throat).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony rak płaskonabłonkowy jamy ustnej, gardła środkowego, gardła dolnego lub krtani
- •Zaawansowane stadium choroby (III, IVA lub IVB)
- •Pacjent kwalifikujący się do standardowego leczenia chemioterapią i radioterapią jednocześnie
- •Obecność przynajmniej jednej zmiany nowotworowej do oceny
✗ Disqualifies
- •Rak pochodzący z nosogardzieli, zatok, gruczołów ślinowych, tarczycy, przytarczyc, skóry lub nieznanego miejsca pierwotnego
- •Inny typ raka niż płaskonabłonkowy
- •Bardzo wczesne lub bardzo zaawansowane stadium choroby, wznowa lub inny rak w tym samym czasie
- •Niemożność przyjęcia chemioterapii opartej na platynie
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 74 Years
- Last updated (source)
- July 2, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (17)
University of Alabama at Birmingham
Birmingham, United States
City of Hope
Duarte, United States
Mayo Clinic
Jacksonville, United States
Moffit Cancer center
Tampa, United States
Emory University
Atlanta, United States
Boston Medical Center
Boston, United States
Montefiore Medical Center
The Bronx, United States
University of North Carolina at Chapel Hill
Chapel Hill, United States
University of Pennsylvania
Philadelphia, United States
Hopital De La Cavale Blanche
Brest, France
Centre Oscar Lambret
Lille, France
Hopital La Timone
Marseille, France
Centre Henri Becquerel
Rouen, France
Gustave Roussy
Villejuif, France
Hiroshima University Hospital
Hiroshima, Japan
Aichi Cancer Center
Nagoya, Japan
Tokyo Medical University Hospital
Tokyo, Japan
Trial contact
Study Contact
Contact information from ClinicalTrials.gov. Contact in English.
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.