RecruitingPhase IIEN originalLeukemia

ALL Backbone in AYAs

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The goal of this research study is to evaluate a chemotherapy regiment for the treatment of newly diagnosed Philadelphia chromosome-negative acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYAs). The names of the study drugs involved in this study are: * blinatumomab (a type of immunotherapy drug) * cyclophosphamide (a type of chemotherapy drug) * cytarabine (a type of antineoplastic agent) * dexamethasone (a type of synthetic glucocorticoid) * doxorubicin (a type of antineoplastic agent) * etoposide (a type of antineoplastic agent) * mercaptopurine (a type of antineoplastic agent) * methotrexate (a type of chemotherapy drug) * pegaspargase (a type of antineoplastic agent) * vincristine (a type of antineoplastic agent)

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Potwierdzona diagnoza ostrej białaczki limfoblastycznej (ALL) bez chromosomu Philadelphia
  • Wiek 18-50 lat
  • Prawidłowe wartości bilirubiny (poniżej 1,4 mg/dL)
  • Gotowość do stosowania skutecznych metod antykoncepcji
  • Wcześniejsze leczenie ograniczało się do sterydów, chemioterapii na drogach oponowych lub jednego cyklu chemioterapii
  • Osoby z białaczką ośrodkowego układu nerwowego mogą brać udział w badaniu

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
51 Years
Last updated (source)
August 17, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Dana Farber Cancer Institute

Boston, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/18/2026.

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