A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The researchers are doing this study to find out whether the combination of botensilimab and balstilimab (BOT/BAL), followed by balstilimab alone, is an effective treatment for people with microsatellite stable (MSS) colorectal cancer or colorectal liver metastases (CRLM) who have measurable residual disease (MRD) after standard treatment with surgery and chemotherapy or total neoadjuvant therapy (TNT).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony rozpoznaniem raka jelita grubego
- •Wiek co najmniej 18 lat
- •Przeszedł całkowitą operację usunięcia guza (R0) wraz z chemioterapią lub innymi standardowymi metodami
- •Wynik badania krwi wykazuje ślady komórek nowotworowych (dodatnia ctDNA)
- •Chętny do udzielenia pisemnej zgody na udział w badaniu
- •Chętny do pobrania próbek krwi i tkanki do badań naukowych
- •Dobry ogólny stan zdrowia (ECOG 0 lub 1)
- •Nowotwór bez tzw. defektu naprawy DNA (non-MSI-H/pMMR)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 22, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (7)
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Rockville Centre, United States
Trial contact
Neil Segal, MD, PhD
Luis Diaz, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/23/2026.
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